Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Thermodynamic description of Eu(NO<sub>3</sub>)<sub>3</sub>-NaNO<sub>3</sub>-H<sub>2</sub>O and Eu(NO<sub>3</sub>)<sub>3</sub>-Mg(NO<sub>3</sub>)<sub>2</sub>-H<sub>2</sub>O systems. Solubility experiments and full dissociation Pitzer models. [PDF]
Häusler F +8 more
europepmc +1 more source
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin +8 more
wiley +1 more source
A Caputo fractional-order SEIHRD model for Ebola: theoretical analysis, sensitivity, bifurcation, and numerical simulations. [PDF]
Malathy R, Krishnan GSS, Loganathan K.
europepmc +1 more source
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
Upper Bounds on the Colloid Separation Efficiency of Diffusiophoresis. [PDF]
Temprano-Coleto F +3 more
europepmc +1 more source
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Exploration of nonclassical symmetries and exact solutions to the (4+1)-dimensional Boiti-Leon-Manna-Pempinelli equation. [PDF]
Ur Rahman M, Akram S, Asif M.
europepmc +1 more source
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
Structural dualities between the Schrödinger equation and its ultra-slow-light counterpart in one spatial and one temporal dimension. [PDF]
Rojas J, Casanova E, Arias M.
europepmc +1 more source

