Results 111 to 120 of about 3,422,228 (336)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Unmasking the Antifungal Activity of Anacardium occidentale Leaf Extract against Candida albicans

Journal of Fungi
Invasive fungal disease causes high morbidity and mortality among immunocompromised patients. Resistance to conventional antifungal drugs and the toxicity associated with high doses highlight the need for effective antifungal therapies.
Luis F. Quejada, Andrea X. Hernandez, Luis C. Chitiva, Claudia P. Bravo-Chaucanés, Yerly Vargas-Casanova, Robson X. Faria, Geison M. Costa, Claudia M. Parra-Giraldo   +7 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

BAG3‐positive pancreatic stellate cells promote migration and invasion of pancreatic ductal adenocarcinoma [PDF]

, 2019
Ye Yuan, Jingyi Jiang, Jia‐Mei Wang, Jia Sun, Chao Li, Bao‐Qin Liu, Jing Yan, Xiaona Meng, Hua‐Qin Wang   +8 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Complete mitogenome of the invasive bivalve Rangia cuneata

Mitochondrial DNA. Part B. Resources, 2019
We sequenced the complete mitogenome of a Baltic Sea specimen of the invasive bivalve Rangia cuneata. The mitogenome is 18,993 bp long and encodes 13 proteins, 2 rRNAs, and 22 tRNAs.
Romain Gastineau, Brygida Wawrzyniak-Wydrowska, Claude Lemieux, Monique Turmel   +3 more
doaj   +1 more source

Antimicrobial susceptibility pattern of invasive pneumococcal isolates in North West Nigeria

Journal of Global Infectious Diseases, 2015
Background: An alarming increase in infections due to penicillin non-susceptible pneumococci (PNSP) has been documented in nearly all countries. Increasingly, PNSP are also resistant to other antibiotics, and a growing number of clinical failures ...
Garba Iliyasu, Abdulrazaq G Habib, Mohammad B Aminu   +2 more
doaj   +1 more source

Management of invasive Allee species [PDF]

, 2017
In this study, we use a discrete, two-patch population model of an Allee species to examine different methods in managing invasions. We first analytically examine the model to show the presence of the strong Allee effect, and then we numerically explore ...
Chan, David, Johnson, D. M., Kent, C. M.
core   +1 more source

Non‐invasive self‐referencing electrochemical sensors for quantifying real‐time biofilm analyte flux [PDF]

, 2008
Eric S. McLamore, D. Marshall Porterfield, M. Katherine Banks   +2 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source