Results 131 to 140 of about 1,697,934 (260)

Pseudolaric Acid B Combats Drug‐Resistant Candida albicans Infection via Dual‐Action Mechanisms of Direct Antifungals and Vaginal Microbiota Restoration

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
We propose a novel therapeutic approach against fungal infection: Pseudolaric acid B directly eradicates C. albicans via Erg11 inhibition and uniquely, restores vaginal microecological homeostasis by promoting probiotic lactobacilli, addressing both the pathogen and the dysbiotic environment.
Tianmeng Shao, Yunshan Zhang, Binqing Xue, Weihua Chu   +3 more
wiley   +1 more source

MSG-10: a Phase 2 study of oral ibrexafungerp (SCY-078) following initial echinocandin therapy in non-neutropenic patients with invasive candidiasis.

Journal of Antimicrobial Chemotherapy, 2019
OBJECTIVES To evaluate the safety and efficacy of two dosing regimens of oral ibrexafungerp (formerly SCY-078), a novel orally bioavailable β-glucan synthase inhibitor, in subjects with invasive candidiasis versus the standard of care (SOC) and to ...
A. Spec, J. Pullman, G. Thompson, W. Powderly, E. Tobin, J. Vázquez, S. Wring, D. Angulo, S. Helou, P. Pappas   +9 more
semanticscholar   +1 more source

Candida carriage in the alimentary tract of liver transplant candidates [PDF]

, 1994
Thirty randomly selected patients with advanced chronic liver disease, which had been evaluated for possible liver transplantation, were sampled endoscopically at 7 alimentary tract locations to assess the frequency and amount of Candida carriage ...
Ho, M, Kusne, S, Pasculle, AW, Starzl, TE, Tobin, D, van Thiel, DH   +5 more
core   +1 more source

Clinical Outcomes of Intra‐Abdominal Candidiasis by Initial Antifungal Therapy

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Background Intra‐abdominal candidiasis (IAC) is a severe and heterogeneous infection associated with significant morbidity and mortality. Objectives To evaluate outcomes of IAC according to initial antifungal therapy and to identify predictors of persistent infection and 30‐day mortality.
M. Albanell‐Fernández, A. Vergara, F. Marco, S. Herrera, M. Tuset, A. Soriano, M. Bodro   +6 more
wiley   +1 more source

Epidemiology of invasive candidiasis before and during the COVID-19 pandemic at a hospital in southeastern Brazil

Journal of Infection in Developing Countries
Introduction: Invasive candidiasis is an important cause of nosocomial infection and recent studies have shown an increase in the number of cases during the coronavirus disease 2019 (COVID-19) pandemic.
Juliana T Gieburowski, Eliane M Psaltikidis, Tiago C Lima, Lucieni de O Conterno, Plinio Trabasso, Maria L Moretti, Mariângela R Resende   +6 more
doaj   +1 more source

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

Haematologica, 2016
The European Conference on Infections in Leukemia (ECIL) provides recommendations for diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various types of infection in patients with hematologic malignancies or ...
F. Tissot, S. Agrawal, L. Pagano, G. Petrikkos, A. Groll, A. Skiada, C. Lass‐Flörl, T. Calandra, C. Viscoli, R. Herbrecht   +9 more
semanticscholar   +1 more source

First Report of Fluconazole‐Resistant Candida parapsilosis Harbouring the G458S ERG11p Substitution in a Brazilian Hospital

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Background Fluconazole‐resistant Candida parapsilosis is a matter of concern. Objectives To investigate fluconazole resistance among Candida parapsilosis complex isolates from patients admitted to three Brazilian hospitals, and to characterise resistance mechanisms and clonal relatedness. Patients/Methods A total of 76 C.
Sarah Santos Gonçalves, Simone Bravim Maifrede, Eduardo Yäkel, Pedro Massaroni Peçanha, Francisco Ozório Bessa‐Neto, Rodrigo Cayô, Anderson Messias Rodrigues, Patricia Muñoz, Pilar Escribano, Jesús Guinea   +9 more
wiley   +1 more source

Azole Resistance in Candida parapsilosis From Patients With Burns in Mexico: A Genomic and Phylogenetic Analysis

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Background Candida species are common causes of nosocomial infections. Candida parapsilosis has emerged as an important pathogen. Mortality rates associated with invasive C. parapsilosis infections range from 14.5% to 47%, with azole resistance estimated between 4% and 15%.
María de Lourdes García‐Hernández, Luis Ángel Nuñez‐García, Jossue Ortíz‐Álvarez, Marco Antonio Delaye‐Martínez, Marlen Flores‐Huacuja, María del Rocío Vazquez‐Olivares, Luis Fernando Espinosa‐Camacho, Gabriela Delgado‐Sapien, María del Rosario Morales‐Espinosa, Noé Becerra‐Lobato, Rafael Franco‐Cendejas, Elvira Garza‐González, Luis Ostrosky‐Zeichner, Tatiana Chávez‐Heres, Melissa Hernández‐Durán, Luis Esaú López‐Jácome, Claudia Adriana Colín‐Castro   +16 more
wiley   +1 more source

MECHANISM OF EPIDEMIC PROCESS OF INVASIVE CANDIDIASIS IN HOSPITAL FOR HIV-INFECTED PATIENTS

Фундаментальная и клиническая медицина, 2018
Aim. To investigate whether contact route is involved in transmission of healthcare-associated invasive candidiasis in HIV-infected patients. Materials and Methods.
IRINA P. Charushina, IRINA V. Feldblum, MARINA V. Kuznetsova, SVETLANA YU. Balandina   +3 more
doaj  

High-resolution mycobiota analysis reveals dynamic intestinal translocation prior to invasive candidiasis

Nature Medicine, 2019
The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and fungi 1 , 2 . Although the composition of bacterial constituents has been linked to immune homeostasis and infectious susceptibility 3 – 7 , the role of non ...
B. Zhai, M. Ola, T. Rolling, T. Rolling, N. Tosini, Sari Joshowitz, E. Littmann, L. Amoretti, E. Fontana, R. Wright, Edwin Miranda, Charlotte A. Veelken, S. Morjaria, S. Morjaria, J. Peled, J. Peled, M. Brink, M. Brink, N. Babady, G. Butler, Y. Taur, Y. Taur, T. Hohl, T. Hohl   +23 more
semanticscholar   +1 more source