Results 71 to 80 of about 1,697,934 (260)

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

VIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng, Jiayun Yang, Shouzhi Yang, Ayizekeranmu Yiming, Wenjun Yu, Yuewei Zhao, Chunmeng Ding, Kexin Meng, Si Gao, Yang Li, Nan Dan, Dandan Feng, Yunhua Xu, Lin Huang, Yongxia Qiao   +14 more
wiley   +1 more source

Efficacy of Fluconazole Prophylaxis on Invasive Candidiasis Infection in Extremely Low Birth Weight Neonates [PDF]

Iranian Journal of Neonatology, 2020
Background: Invasive candidiasis infection is one of the main life-threatening problems for extremely low birth weight (ELBW) neonates who are in the neonatal intensive care unit (NICU).
Hosein Dalili, Nikoo Niknafs, Mamak Shariat, Raheleh Moradi, Hasti Charousaei, Elaheh Amini, Roksana Moeini, Afsaneh Akhondzadeh, Amir Naddaf   +8 more
doaj   +1 more source

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

Critical Care, 2019
BackgroundThe objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe.MethodsA multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries ...
M. Bassetti, D. Giacobbe, A. Vena, C. Trucchi, F. Ansaldi, M. Antonelli, V. Adámková, C. Alicino, M. Almyroudi, E. Atchade, A. Azzini, N. Carannante, A. Carnelutti, S. Corcione, A. Cortegiani, G. Dimopoulos, S. Dubler, J. García-Garmendia, M. Girardis, O. Cornely, Stefano Ianniruberto, B. Kullberg, K. Lagrou, Clément Le bihan, R. Luzzati, M. Malbrain, M. Merelli, A. J. Marques, I. Martín-Loeches, A. Mesini, J. Paiva, M. Peghin, S. Raineri, R. Rautemaa‐Richardson, J. Schouten, P. Brugnaro, H. Spapen, P. Tasioudis, J. Timsit, V. Tisa, M. Tumbarello, Charlotte H S B van den Berg, B. Veber, M. Venditti, G. Voiriot, J. Wauters, P. Montravers   +46 more
semanticscholar   +1 more source

Virulence assessment of six major pathogenic Candida species in the mouse model of invasive candidiasis caused by fungal translocation

Scientific Reports, 2020
Gastrointestinal colonization has been considered as the primary source of candidaemia; however, few established mouse models are available that mimic this infection route.
T. Hirayama, T. Miyazaki, Y. Ito, M. Wakayama, K. Shibuya, K. Yamashita, T. Takazono, Tomomi Saijo, Shintaro Shimamura, Kazuko Yamamoto, Y. Imamura, K. Izumikawa, K. Yanagihara, S. Kohno, H. Mukae   +14 more
semanticscholar   +1 more source

Identification of superficial Candida albicans germ tube antigens in a rabbit model of disseminated candidiasis. A proteomic approach [PDF]

, 2014
The diagnosis of invasive candidiasis remains a clinical challenge. The detection by indirect immunofluorescence of Candida albicans germ-tube-specific antibodies (CAGTA), directed against germ-tube surface antigens, is a useful diagnostic tool that ...
Aranzazu Sáez-Rosón, María-Dolores Moragues, María-Jesús Sevilla   +2 more
core   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis

Clinical and Developmental Immunology, 2008
Invasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical symptoms and a definitive ...
Ana Laín, Natalia Elguezabal, Elena Amutio, Iñigo Fernández de Larrinoa, María Dolores Moragues, José Pontón   +5 more
doaj   +1 more source

Voriconazole treatment of Candida tropicalis meningitis: persistence of (1,3)-b-D-glucan in the cerebrospinal fluid is a marker of clinical and microbiological failure [PDF]

, 2016
Introduction: Infections are still the most common complications of cerebral shunt procedures. Even though fungal etiologies are considered to be rare, they are associated with significant morbidity and mortality.
Brunetti, Grazia, Ceccarelli, Giancarlo, Fallani, Stefania, Ghezzi, Maria Cristina, Marsiglia, Carolina, Novelli, Andrea, Raponi, Giammarco, Venditti, Mario   +7 more
core   +2 more sources

Pathogenesis of invasive candidiasis

Current Opinion in Critical Care, 2010
Disseminated candidiasis remains a life-threatening disease in the ICU. The development of invasive disease with Candida albicans is dependent on multiple factors, such as colonization and efficient host defense at the mucosa. In the present review, we describe the host defense mechanisms against Candida that are responsible for counteracting mucosal ...
Veerdonk, F.L. van de, Kullberg, B.J., Netea, M.G.   +2 more
openaire   +3 more sources

Oral Health Care Services, Barriers and Enablers to Maintaining Good Oral Health in Motor Neurone Disease: A Scoping Review

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives The objective of this scoping review was to map existing literature on oral health and related care in individuals with Motor Neurone Disease (MND). Specifically, the review aimed to identify barriers and facilitators to maintaining oral hygiene, summarise available clinical guidelines and patient‐facing resources, and examine how ...
Mariam A. Khokhar, Lucy A. O'Malley, Anne‐Marie Glenny, Xiaohui Chen   +3 more
wiley   +1 more source