Results 1 to 10 of about 382,917 (208)

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma

Nature Communications, 2022
Progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) remains poorly understood. Here, the authors analyse over 2700 micro-dissected samples using transcriptomics to identify genes that characterise different stages of DCIS ...
Clare A. Rebbeck, Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herbert K. Lyerly, Gregory J. Hannon   +11 more
doaj   +2 more sources

Case Report: Sneaky DCIS-like invasive ductal carcinoma of the breast in the setting of extensive DCIS [PDF]

Frontiers in Medicine
In most cases, invasive ductal carcinoma (IDC) of the breast is identifiable when it presents with classic infiltrative growth patterns. However, a subset of IDC can present in a very sneaky way, significantly mimicking the appearance of ductal carcinoma
Chong Chen, Chong Chen, Yateng Tie, Xinjuan Zhang, Niuniu Hou, Niuniu Hou, Yun Song, Yun Song, Dong Ren, Dong Ren   +9 more
doaj   +2 more sources

Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast

BMC Research Notes, 2018
Objectives The aim of this study was to determine the frequency of metaplastic breast carcinoma and invasive micropapillary carcinoma in our population and also to compare the clinico-pathologic features of metaplastic breast carcinoma and invasive ...
Atif Ali Hashmi, Saher Aijaz, Raeesa Mahboob, Saadia Mehmood Khan, Muhammad Irfan, Narisa Iftikhar, Mariam Nisar, Maham Siddiqui, Muhammad Muzzammil Edhi, Naveen Faridi, Amir Khan   +10 more
doaj   +2 more sources

A case report of coexistence of invasive ductal carcinoma and malignant phyllodes tumor in a single breast mass [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022
Introduction: Coexistence of malignant phyllodes tumor and invasive ductal carcinoma in a breast lesion is a very rare medical condition. In this study, a case of coexistence of invasive ductal carcinoma and malignant phyllodes tumor in a single breast ...
Mahsa Akbari Oryani, Zahra Nikfarjam
doaj   +1 more source

Association of clinico-pathological and immunohistochemical prognostic parameters with presence of ductal carcinoma in-situ in an invasive ductal carcinoma of breast

Journal of Pathology of Nepal, 2023
Background: The clinical outcome of breast carcinoma varies in each individual due to its molecular heterogeneity. There is a rising interest in whether the associated ductal carcinoma in-situ in invasive ductal carcinoma of breast affects the prognosis ...
Dhivya Balaiya, Anitha Chellam Annadurai, Jayakarthiga Subbiah Rajasekaran   +2 more
doaj   +1 more source

Neoadjuvant Chemotherapy or Endocrine Therapy for Invasive Ductal Carcinoma of the Breast With High Hormone Receptor Positivity and Human Epidermal Growth Factor Receptor 2 Negativity

JAMA Network Open, 2021
Key Points Question Is neoadjuvant endocrine therapy (NET) an alternative treatment for neoadjuvant chemotherapy (NACT) in patients with invasive ductal carcinoma (IDC) of the breast who have strong hormone receptor (HR) positivity and human epidermal ...
Jiaqiang Zhang, Chang-Yun Lu, Ho‐Min Chen, Szu-Yuan Wu   +3 more
semanticscholar   +1 more source

Breast Invasive Ductal Carcinoma Classification on Whole Slide Images with Weakly-Supervised and Transfer Learning

bioRxiv, 2021
Invasive ductal carcinoma (IDC) is the most common form of breast cancer. For the non-operative diagnosis of breast carcinoma, core needle biopsy has been widely used in recent years which allows evaluation of both cytologic and tissue architectural ...
F. Kanavati, M. Tsuneki
semanticscholar   +1 more source

Potential biomarkers of ductal carcinoma in situ progression

BMC Cancer, 2020
Background Ductal carcinoma in situ is a non-obligate precursor of invasive breast carcinoma and presents a potential risk of over or undertreatment. Finding molecular biomarkers of disease progression could allow for more adequate patient treatment.
Raquel Spinassé Dettogni, Elaine Stur, Ana Carolina Laus, René Aloísio da Costa Vieira, Márcia Maria Chiquitelli Marques, Iara Viana Vidigal Santana, José Zago Pulido, Laura Fregonassi Ribeiro, Narelle de Jesus Parmanhani, Lidiane Pignaton Agostini, Raquel Silva dos Reis, Eldamária de Vargas Wolfgramm dos Santos, Lyvia Neves Rebello Alves, Fernanda Mariano Garcia, Jéssica Aflávio Santos, Diego do Prado Ventorim, Rui Manuel Reis, Iúri Drumond Louro   +17 more
doaj   +1 more source

Whole-Exome Sequencing Analysis of the Progression from Non–Low-Grade Ductal Carcinoma In Situ to Invasive Ductal Carcinoma

Clinical Cancer Research, 2020
Purpose: Ductal carcinoma in situ (DCIS) is a nonobligate precursor of invasive breast cancer. Here, we sought to investigate the level of intralesion genetic heterogeneity in DCIS and the patterns of clonal architecture changes in the progression from ...
F. Pareja, David N. Brown, J. Y. Lee, A. Da Cruz Paula, P. Selenica, R. Bi, F. Geyer, A. Gazzo, E. D. da Silva, M. Vahdatinia, A. Stylianou, L. Ferrando, H. Wen, J. Hicks, B. Weigelt, J. Reis-Filho   +15 more
semanticscholar   +1 more source

Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]

, 2016
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio, Argento, Giuseppe, Campanella, L, Cunsolo, G, DI STEFANO, Domenica, Lombardi, Augusto, Maggi, Stefano, Mastrangeli, Mr, Mattei, Ms, Stanzani, G, Vitale, Valeria   +10 more
core   +1 more source