Results 101 to 110 of about 1,357,862 (296)

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

Granulomatous reaction associated with breast carcinoma: A report of two cases

Saudi Journal of Medicine and Medical Sciences, 2014
The presence of a granulomatous reaction in association with a breast carcinoma is a rare phenomenon. We present two cases of breast carcinoma, invasive ductal and invasive lobular carcinoma in which a non-caseating granulomatous response was present ...
Timor Alalshee, Tahira Hamed, Sheikh M Shafi   +2 more
doaj   +1 more source

Independent predictors of breast malignancy in screen-detected microcalcifications: biopsy results in 2545 cases [PDF]

, 2011
Background: Mammographic microcalcifications are associated with many benign lesions, ductal carcinoma in situ (DCIS) and invasive cancer. Careful assessment criteria are required to minimise benign biopsies while optimising cancer diagnosis.
S Pieterse, P Downey, Farshid, G., Sullivan, T., Downey, P., Gill, P., G Farshid, T Sullivan, P G Gill, Pieterse, S.   +9 more
core   +1 more source

Achievement of the Ideal Outcome After Pancreatectomy for Pancreatic Ductal Adenocarcinoma Is Associated With Earlier Initiation and Higher Completion Rates of Adjuvant Chemotherapy and Improved Long‐Term Survival

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Ideal Outcome is a composite quality indicator reflecting optimal postoperative course after pancreatic surgery. This study aimed to clarify the prognostic significance of achieving the Ideal Outcome and its influence on the initiation and completion of adjuvant chemotherapy.
Ryosuke Fukushima, Kenichiro Araki, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Shunsuke Kawai, Mariko Tsukagoshi, Takamichi Igarashi, Norio Kubo, Ken Shirabe   +9 more
wiley   +1 more source

Protein kinase C alpha expression in normal breast, ductal carcinoma in situ and invasive ductal carcinoma

, 2004
The purpose of this study was to determine if Protein Kinase C alpha (PKC alpha) is altered in expression or localisation in normal breast, ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC). We obtained 14 mixed cases of invasive ductal
Pearson, J. M., Bishop, H. M., Winstanley, J. H R, Garrod, D. R., Ainsworth, P. D.   +4 more
core   +1 more source

ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research

Advanced Intelligent Systems, EarlyView.
This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu, Markus Breunig, Arpad Varga, Bianka Bosch, Jessica Lindenmayer, Anjan T. Kanakappady, Kevin Achberger, Natalia Pashkovskaia, Alexander Kleger, Stefan Liebau, Stefanie Klingenstein, Moritz Klingenstein   +11 more
wiley   +1 more source

Complications and Clinical Outcomes Following Modified Endoscopic Denker's With Pyriform Aperture Preservation: A Prospective Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The modified endoscopic Denker's (MED) approach provides access to all maxillary sinus (MS) walls for resection of various MS and retromaxillary pathologies, but the anteromedial maxilla has historically been resected. This study determined complication rates and outcomes following MED with pyriform aperture (PA) preservation ...
Yasser Almansour, Lane Donaldson, Khaled Kashlan, Swapna Vemuri, Jun Jin, John R. Craig   +5 more
wiley   +1 more source

Immunohistochemical Expression of E-cadherin in Sclerosing Adenosis, Ductal Carcinoma in Situ and Invasive Ductal Carcinoma of the Breast

, 2010
E-cadherin (EC) is an important glycoprotein cell-adhesion molecule that appears to play a significant role in the progression of breast lesions. the objective of this study was to evaluate EC expression in sclerosing adenosis, ductal carcinoma in situ ...
Pinho-Sobral, Andre Luis, Ferreira-Filho, Celso Fires, Facina, Gil [UNIFESP], Da Silva, Benedito Borges, Dos Santos, Alesse Ribeiro, Gebrim, Luiz Henrique [UNIFESP], Lopes-Costa, Pedro Vitor, De Vasconcelos-Valenca, Rodrigo Jose, Alencar, Airlane Pereira   +8 more
core   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

Distinction of invasive lobular carcinoma, invasive ductal carcinoma, and healthy breast tissue in vivo with L-COSY at 3T [PDF]

, 2011
The presence of a choline resonance at 3.23ppm has been shown by several groups to be a diagnostic marker for breast cancer in vivo. For review see 1 . A second resonance at 3.28ppm is recorded in some healthy volunteers and lactating mothers. However in
Mountford, C.E., Stanwell, P., Kaiser, W.A., Box, H.N., Lin, A., Gombos, E., Ramadan, S., Baltzer, P.   +7 more
core