Results 131 to 140 of about 83,920 (307)

Outcomes and Risk Factors in Oncologic Temporal Bone Surgery: A Head and Neck‐Specific NSQIP Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Advanced temporal bone and parotid gland malignancies are rare and difficult to manage. However, complications of oncologic temporal bone surgery have not been systematically categorized. We aim to detail the postoperative outcomes of lateral temporal bone resection (LTBR) and mastoidectomy for otologic oncology patients, and ...
Bailey H. Duhon   +5 more
wiley   +1 more source

Metamorphoses in pancreatic cancer precursors: the role of simple mucinous cysts†

open access: yesThe Journal of Pathology, EarlyView.
Abstract Pancreatic cystic lesions present a unique opportunity to identify and potentially prevent pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid tumors. Until now, research has primarily focused on intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), whose potential for malignant transformation ...
Paolo Riccardo Camisa   +3 more
wiley   +1 more source

Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs

open access: yesThe Prostate, EarlyView.
ABSTRACT Background The dog is the only large mammal, other than humans, that commonly develops spontaneous prostate cancer (PCa) and is, therefore, considered a valuable model for comparative studies. Estrogens are critical for normal prostate development and contribute to prostatic carcinogenesis in men.
Jennifer Lothion‐Roy   +9 more
wiley   +1 more source

Diagnostic Value of Rapid On‐Site Evaluation Combined With Prostate Biopsy in Prostate Cancer

open access: yesThe Prostate, EarlyView.
ABSTRACT Objective To investigate the application value of Rapid On‐Site Evaluation (ROSE) in prostate biopsy. Methods All consecutive subjects who attended our clinic to underwent magnetic resonance imaging (MRI)‐ultrasound fusion biopsy due to highly suspicious findings on MRI for prostate cancer (PCa) and met the inclusion criteria were enrolled ...
Hong Ma   +5 more
wiley   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Invasive Ductal Carcinoma within a Benign Phyllodes Tumor

open access: hybrid, 2017
Nancy Panko   +3 more
openalex   +2 more sources

Potential clinical utility of small extracellular vesicles derived from head and neck tumours

open access: yesVIEW, EarlyView.
Small extracellular vesicles (EVs) carry selective protein cargoes that reflect tumour cell status, making them valuable for biomarker discovery. This study compared EV proteomes from head and neck cancer (HNC) tumour tissue, saliva and plasma. Over 60% of proteins were shared across all sources, with enrichment in cancer‐related pathways such as ...
Abolfazl Jangholi   +6 more
wiley   +1 more source

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