Pan‐cancer analysis reveals molecular signatures for predicting matrix stiffness in solid tumors
What's new? Tumor matrix stiffness plays a critical role in cancer progression, metastasis, and therapy resistance. Here, the authors leveraged tumor RNA‐seq data to identify molecular signatures of mechanical properties across various cancer types and build a computational model for predicting tumor matrix stiffness.
Gongyu Tang +6 more
wiley +1 more source
Prediction model for assessing HER2 status patient with invasive ductal carcinoma based on clinical parameters and ultrasound features: a dual-center study. [PDF]
Zhou L +10 more
europepmc +1 more source
The Space Within: How Architected Voids Promote Tissue Formation
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Neoadjuvant chemotherapy for primary invasive ductal carcinoma of the nipple: A case report. [PDF]
Sun K, Zhu M, Chen G, Liu B.
europepmc +1 more source
Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley +1 more source
Concurrent Invasive Ductal Carcinoma and Pancreatic Intraepithelial Neoplasia in Duodenal Heterotopic Pancreas: A Case Report. [PDF]
Al Harthi S, Al-Masqari M.
europepmc +1 more source
Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer
Potential biomarkers for the development of targeted radionuclide therapy that can be employed in the treatment of breast cancer have been summarised in the review. They include receptor markers of ER, PR and HER2, as well as other markers of Trop2, PD‐1, EGFR, GRPR and PSMA.
Yujing Tan +3 more
wiley +1 more source
Leptomeningeal Disease Secondary to Invasive Ductal Carcinoma of the Breast: A Rapidly Progressive and Fatal Complication. [PDF]
Dhawan S +4 more
europepmc +1 more source
A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava +4 more
wiley +1 more source

