Results 101 to 110 of about 74,757 (299)

Anidulafungin in the treatment of invasive fungal infections

Therapeutics and Clinical Risk Management, 2008
Kathryn Sabol, Tawanda GumboUniversity of Texas Southwestern Medical Center, Dallas, TX, USAAbstract: More antifungal agents have reached clinical use in the past two decades than at any other time.
Kathryn Sabol, Tawanda Gumbo
doaj  

Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study)

Haematologica, 2015
Correct definition of the level of risk of invasive fungal infections is the first step in improving the targeting of preventive strategies. We investigated the potential relationship between pre-hospitalization exposure to sources of fungi and the ...
Morena Caira, Anna Candoni, Luisa Verga, Alessandro Busca, Mario Delia, Annamaria Nosari, Cecilia Caramatti, Carlo Castagnola, Chiara Cattaneo, Rosa Fanci, Anna Chierichini, Lorella Melillo, Maria Enza Mitra, Marco Picardi, Leonardo Potenza, Prassede Salutari, Nicola Vianelli, Luca Facchini, Monica Cesarini, Maria Rosaria De Paolis, Roberta Di Blasi, Francesca Farina, Adriano Venditti, Antonella Ferrari, Mariagrazia Garzia, Cristina Gasbarrino, Rosangela Invernizzi, Federica Lessi, Annunziata Manna, Bruno Martino, Gianpaolo Nadali, Massimo Offidani, Laura Paris, Vincenzo Pavone, Giuseppe Rossi, Antonio Spadea, Giorgina Specchia, Enrico Maria Trecarichi, Adriana Vacca, Simone Cesaro, Vincenzo Perriello, Franco Aversa, Mario Tumbarello, Livio Pagano   +43 more
doaj   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, EarlyView.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Outcomes of Invasive Fungal Infections Treated with Isavuconazole: A Retrospective Review. [PDF]

Pathogens
Background: Isavuconazole (ISA) has a favorable side effect profile that makes it attractive for treatment of invasive fungal infections (IFI). It carries FDA approval for invasive aspergillosis and mucormycosis, but there are fewer data for other ...
Gow-Lee V, Abu Saleh OM, Harris CE, Gile JJ, Akhiyat N, Chesdachai S.   +5 more
europepmc   +2 more sources

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source

Amphotericin B lipid complex: treatment of invasive fungal infections in patients refractory to or intolerant of amphotericin B deoxycholate [PDF]

, 2008
PH ChandrasekarDivision of Infectious Diseases, Department of Internal Medicine, Wayne State University, Karmanos Cancer Institute, Detroit, MI, USAAbstract: Amphotericin B lipid complex (ABLC) was introduced in the late 1990s as a less toxic alternative
PH Chandrasekar
core  

Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units : protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project [PDF]

, 2019
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Vazquez, J.A., Martin-Loeches, I., Garnacho-Montero, J, Rello, J., Timsit, JF, Muñoz, P, Arıkan Akdagli, S, Calandra, T., Alastruey-Izquierdo, A, Azoulay, E, Koehler, P, Vazquez, JA, De Waele, J.J., Arikan-Akdagli, S., Bassetti, M, Rebuffi, C, Dimopoulos, G., Cornely, O, Blot, Stijn, Poulakou, G, Hoenigl, M, Rebuffi, C., Lass-Flörl, C., Kullberg, BJ, Blot, S.I., de Lange, D.W., Koehler, P., Kullberg, B.J., De Waele, Jan, Grecchi, C, Grecchi, C., Azoulay, E., Zuccaro, V, Taccone, FS, Garnacho-Montero, J., Maertens, J, Torres, A, Alastruey-Izquierdo, A., Cuenca-Estrella, M, Hoenigl, M., Taccone, F.S., Righi, E., Muñoz, P., Kanj, SS, Scudeller, L, Poulakou, G., Kanj, S.S., Sanguinetti, M., De Rosa, FG, Akova, M., Torres, A., Martin-Loeches, I, Lamoth, F, De Rosa, F.G., Timsit, J.F., Sanguinetti, M, Lamoth, F., Maertens, J., Calandra, T, Cornely, O.A., Scudeller, L., Akova, M, Agvald-Ohman, C., Lass-Flörl, C, Zuccaro, V., Giacobbe, D.R., Dimopoulos, G, Agvald-Ohman, C, Righi, E, de Lange, DW, Giacobbe, DR, Rello, J, Bassetti, M., Cuenca-Estrella, M.   +73 more
core   +1 more source

Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease

Medical Mycology Case Reports, 2018
We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome.
Fabian Leo, Michael Zeh, Annegret Prothmann, Oliver Kurzai, Sylke Kurz, Christian Grohé   +5 more
doaj   +1 more source