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Pathogenesis of invasive fungal infections
Current Opinion in Infectious Diseases, 2013Invasive fungal infection (IFI) is increasingly being recognized as a significant cause of morbidity and mortality in immunosuppressed patients. This review focuses on the latest literature reports concerning the pathogenesis of IFI in this population.New virulence factors of Candida and Aspergillus have recently been identified.
Carolina, Garcia-Vidal +2 more
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Immunodiagnosis of invasive fungal infections
Medical Mycology, 1994(1994). Immunodiagnosis of invasive fungal infections. Journal of Medical and Veterinary Mycology: Vol. 32, No. sup1, pp. 239-252.
L, De Repentigny +5 more
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Immunomodulation of invasive fungal infections
Infectious Disease Clinics of North America, 2003Genetic and acquired (disease- or therapy- related) host immune factors increase the risk for IFIs. In addition to antifungal drug therapy, modulation of host defenses by the use of HGFs and IFN-gamma has been supported by extensive in vitro and in vivo preclinical data.
Emmanuel, Roilides +3 more
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Therapy of invasive fungal infections
The Netherlands Journal of Medicine, 1999During the past decades, the incidence and severity of invasive fungal infections has been increasing. These events have lead to the development of new antifungal agents, and amphotericin B no longer is the standard therapy for a variety of invasive mycoses. Fluconazole has become the drug of choice for treatment of C.
Kullberg, B.J., Pauw, B.E. de
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Glucocorticoids and invasive fungal infections
The Lancet, 2003Since the 1990s, opportunistic fungal infections have emerged as a substantial cause of morbidity and mortality in profoundly immunocompromised patients. Hypercortisolaemic patients, both those with endogenous Cushing's syndrome and, much more frequently, those receiving exogenous glucocorticoid therapy, are especially at risk of such infections.
Michail S, Lionakis +1 more
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Clinical Experience in Invasive Fungal Infections
Clinical Drug Investigation, 2013Lung infections caused by invasive filamentous fungi are very rare conditions in AIDS, but must be considered in patients with profound immune suppression especially in the presence of additional risk factors, such as hematologic malignancies, corticosteroid therapy, neutropenia, and chemotherapy. The authors report a case of dual lung infection caused
Pacheco, P +4 more
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Combat-Related Invasive Fungal Wound Infections
Military Medicine, 2022ABSTRACT Introduction During Operation Enduring Freedom in Afghanistan, an outbreak of combat-related invasive fungal wound infections (IFIs) emerged among casualties with dismounted blast trauma and became a priority issue for the Military Health System.
Ret Carlos J, Rodriguez +6 more
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Archives of Internal Medicine, 1983
• Serologic tests are useful in providing a presumptive diagnosis of invasive fungal infection, allowing early institution of specific therapy. The judicious use of these serologic tests for circulating antibodies or antigens also may aid in analyzing response to treatment and in assessing prognosis.
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• Serologic tests are useful in providing a presumptive diagnosis of invasive fungal infection, allowing early institution of specific therapy. The judicious use of these serologic tests for circulating antibodies or antigens also may aid in analyzing response to treatment and in assessing prognosis.
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2016
Upon completion of the chapter, the reader will be able to: 1. Differentiate epidemiologic differences and host risk factors for acquisition of primary and opportunistic invasive fungal diseases. 2. Recommend appropriate empiric or targeted antifungal therapy for the treatment of invasive fungal disease. 3.
Lewis RE, Rogers PD
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Upon completion of the chapter, the reader will be able to: 1. Differentiate epidemiologic differences and host risk factors for acquisition of primary and opportunistic invasive fungal diseases. 2. Recommend appropriate empiric or targeted antifungal therapy for the treatment of invasive fungal disease. 3.
Lewis RE, Rogers PD
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Overview of Invasive Fungal Infections
2012The incidence of invasive fungal infections (IFIs) has seen a marked increase in the last two decades. This is especially evident among transplant recipients, patients suffering from AIDS, in addition to those in receipt of immunosuppressive therapy.
Nina L, Tuite, Katrina, Lacey
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