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Invasive Pneumococcal and Meningococcal Disease
Infectious Disease Clinics of North America, 2019This review focuses on current knowledge of the epidemiology, prevention, and treatment of invasive pneumococcal (IPD) and meningococcal disease (IMD). IPD decreased significantly with the introduction of effective conjugate vaccines but is on the rise again.
Deirdre, Fitzgerald, Grant W, Waterer
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Invasive meningococcal disease: a disease of the endothelial cells
Trends in Molecular Medicine, 2014Neisseria meningitidis is an extracellular pathogen, which, once in the bloodstream, has the ability to form microcolonies on the apical surface of endothelia. Pathogen interaction with microvessels is mediated by bacterial type IV pili and two receptors on endothelial cells: CD147 and the β2-adrenoceptor.
Coureuil, Mathieu +3 more
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