Results 251 to 260 of about 42,409 (308)

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

Advanced Science, EarlyView.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan, Dan Guo, Songtao Li, Jinmiao Tian, Chaotong Zhang, Zhuoyu Li   +5 more
wiley   +1 more source

Clinical Characteristics and Prognostic Factors in Patients with Gestational Trophoblastic Neoplasia: A Single-Center Study Comparing Ultra-High-Risk and Other Risk Groups. [PDF]

Cancers (Basel)
Ruengsaen A, Sethasathien S, Tantipalakorn C, Charoenkwan K, Suprasert P, Srisomboon J, Tongsong T.   +6 more
europepmc   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Role of mechanical hysteroscopic tissue removal system in post-molar gestational trophoblastic neoplasia management: case report and literature review. [PDF]

J Surg Case Rep
Schoenen S, Delbecque K, Kridelka F, Hanocq F, Goffin F, Nervo P.   +5 more
europepmc   +1 more source

Elucidation of the role of XBP1 in the progression of complete hydatidiform mole to invasive mole through RNA-seq

Mayu Shibata, Kosuke Yoshida, Akira Yokoi, Hironori Suzuki, Yusuke Yamamoto, Masami Kitagawa, Eri Asano‐Inami, Yuko Yasui, Yuki Nishiko, Masato Yoshihara, Satoshi Tamauchi, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama   +15 more
openalex   +1 more source

Chirality Regulates Stem Cell Fate and Promotes Corneal Epithelial Regeneration via Manipulating Notch Pathway

Advanced Science, EarlyView.
Chirality governs the limbal epithelial stem cell fate. Right‐handed chirality enhances cell proliferation and differentiation, while left‐handed chirality partially maintains cell stemness. By activating the Notch pathway, 3D right‐handed chiral hydrogel offers a drug‐free and cell‐free strategy for effective corneal regeneration.
Shiding Li, Yu Zhao, Junzhao Chen, Beibei Wu, Nianxuan Wu, Hao Sun, Liangbo Chen, Chuanliang Feng, Yao Fu   +8 more
wiley   +1 more source

Complete Molar Pregnancy in a 50-Year-Old Postmenopausal Woman. [PDF]

Cureus
Vural B, Kaymak SD, Turhan B, Kavak RP, Yüksel D.   +4 more
europepmc   +1 more source

Hydatidiform mole identification using non‐invasive single‐cell sequencing of fetal circulating extravillous trophoblasts isolated from maternal blood

Chiara Mangano, A. Doffini, Claudio Forcato, Simona Boito, D. Lattuada, E. Giovannone, Genny Buson, Jon Hyett, Thomas J. Musci, Francesca Romana Grati   +9 more
openalex   +1 more source

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Corrigendum to “miR-196b inhibits cell migration and invasion through targeting MAP3K1 in hydatidiform mole” [Biomed. Pharmacother. 113 (2019) 108760]

Zhenzhen Guo, Linlin Sui, Jia Qi, Qiannan Sun, Yuefei Xu, Na Zou, Yunpeng Xie, Ying Kong   +7 more
openalex   +1 more source