Abstract Globally, the highest incidence of meningococcal meningitis occurs within the African meningitis belt, spanning 26 countries across sub‐Saharan Africa. Meningococcal meningitis incidence is highly seasonal in this region specifically, with outbreaks mostly occurring during the dry season, characterized by low rainfall and atmospheric humidity,
Molly Cliff +6 more
wiley +1 more source
Effectiveness of vaccinating household contacts in addition to chemoprophylaxis after a case of meningococcal disease: a systematic review. [PDF]
SUMMARYWe performed a systematic review to estimate the effectiveness of vaccination, in addition to chemoprophylaxis, in preventing meningococcal disease among household contacts. Medline, EMBASE, EMGM, and EUIBIS were used for data collection.
Stuart, J.M. +12 more
core +1 more source
Serotype 3 pneumococcal pleural empyema: a case report and review of the epidemiology
Serotype 3 pneumococcal infection can cause severe invasive disease, even in immunocompetent adults, and is potentially preventable by vaccination. Invasive pneumococcal disease caused by serotype 3 is currently the most frequent serotype found in adults
Maja Thoustrup Legardt Johansen +3 more
doaj +1 more source
Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo +8 more
doaj +1 more source
Molecular epidemiology of paediatric invasive pneumococcal disease in Andalusia, Spain
This study aimed to assess the impact of the introduction of pneumococcal conjugate vaccine 13 (PCV13) on the molecular epidemiology of invasive pneumococcal disease (IPD) in children from Andalusia.
Santos Pérez, José Luis +7 more
core +1 more source
American Journal of Hematology, Volume 101, Issue 10, Page 2654-2658, October 2026.
Alma Al Sibaaie +12 more
wiley +1 more source
Estimating the transmission parameters of pneumococcal carriage in households [PDF]
This paper analyses Streptococcus pneumoniae transmission dynamics in households using longitudinal data on pneumococcal (Pnc) carriage in the United Kingdom. Ten consecutive swabs were taken at 4-week intervals from all members of 121 households.
Medley, Graham +5 more
core +1 more source
A mathematical model of serotype replacement in pneumococcal carriage following vaccination. [PDF]
A number of childhood vaccination programmes have recently introduced vaccination against Streptococcus pneumoniae, the pneumococcus, a major cause of pneumonia and meningitis.
Bottomley, Christian +4 more
core +1 more source
Pneumococcal infections are a major cause of morbidity and mortality in developing countries. The introduction of pneumococcal conjugate vaccines (PCVs) has dramatically reduced the incidence of pneumococcal diseases. PCVs are not currently being used in
N. Ramdani-Bouguessa +13 more
doaj +1 more source
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
Mitchell, T.J. +28 more
core +1 more source

