Results 231 to 240 of about 11,123,027 (272)

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

open access: yesAdvanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou   +11 more
wiley   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

open access: yesAdvanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang   +9 more
wiley   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang   +17 more
wiley   +1 more source

Invasive Species [PDF]

open access: possibleThe Missouri Review
This is a documentation of practice-led research into the proliferation of invasive species, a phenomenon analogous to colonialism and its accompanying systemic extraction and displacement of bodies, goods, and earth materials. Sylvia Wynter attributes this spread to the Enlightenment era centering of European man as the hierarchical pinnacle of ...
Yilun Zhao, Chunyuan Diao, Zhijie Zhou
semanticscholar   +16 more sources

Invasive Species

The Massachusetts Review, 2023
Abstract Invasive species are species that have been introduced from elsewhere and now cause economic or environmental harm. Such introductions were formerly sometimes deliberate, for example, for biological control, but now they are largely accidental, and because of increased global trade, they continue to increase. A small fraction of
Petr PYŠEK, David M. RICHARDSON
semanticscholar   +5 more sources

Invasive Species

2017
With climate change and increasing globalisation of trade and travel, the risks presented by invasive pests and pathogens to natural environments, agriculture and economies have never been greater, and are only increasing with time. Governments world-wide are responding to these increased threats by strengthening quarantine and biosecurity.
Greimler, Josef   +4 more
openaire   +3 more sources

Invasive Species

Journal of Herpetological Medicine and Surgery, 2008
ABSTRACT Invasive species have a negative impact on local wildlife, at times even causing extinction. Released captive or non-native species can introduce exotic diseases to wildlife. Owners must be very diligent to have enclosures/cages that prevent escape of reptile and amphibian pets.
John B. Heppner   +17 more
  +4 more sources

Invasive Species

2022
AbstractInvasive species have significant effects on biodiversity. Genetics provides insights important for eradication and control crucial for conservation. Invasive species can be successful despite bottlenecks because of increased genetic diversity following hybridization or multiple introductions, rapid evolutionary change, lack of natural enemies,
Fred W. Allendorf   +4 more
openaire   +1 more source

From eDNA to citizen science: emerging tools for the early detection of invasive species

, 2020
B invasions are one of many forms of anthropogenic change that threaten biodiversity, the structure and function of ecosystems, human health, and the global economy (Ehrenfeld 2010; Bradshaw et al. 2016).
E. Larson   +15 more
semanticscholar   +1 more source

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