Results 61 to 70 of about 1,028,309 (361)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Minimally invasive strabismus surgery [PDF]

Expert Review of Ophthalmology, 2009
In strabismus surgery, the post-operative visibility of the procedure and level of patient discomfort will mainly be influenced by the number and type of muscles operated on and the type and location of the conjunctival openings. For strabismus surgeries minimising tissue disruption, the term minimally invasive strabismus surgery (MISS) has been ...
openaire   +4 more sources

Early and Late Reoperation Rates With Various MIS Techniques for Adult Spinal Deformity Correction. [PDF]

, 2018
Study designA multicenter retrospective review of an adult spinal deformity database.ObjectiveWe aimed to characterize reoperation rates and etiologies of adult spinal deformity surgery with circumferential minimally invasive surgery (cMIS) and hybrid ...
Akbarnia, Behrooz A, Anand, Neel, Chou, Dean, Deviren, Vedat, Eastlack, Robert K, International Spine Study Group, Kanter, Adam S, Mummaneni, Praveen V, Mundis, Gregory M, Nguyen, Stacie, Nunley, Pierce, Okonkwo, David O, Park, Paul, Srinivas, Ravi, Uribe, Juan S   +14 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Meta-analysis of maternal and neonatal outcomes of cannabis use in pregnancy current to March 2024

Maternal Health, Neonatology and Perinatology
Importance Following expansive legalization of cannabis in many parts of the United States, cannabis use in pregnancy has increased several fold. There is a pressing need to understand the maternal and neonatal outcomes associated with this exposure ...
Katelyn Sainz, Hollie Ulibarri, Amanda Arroyo, Daniela Gonzalez Herrera, Brooke Hamilton, Kate Ruffley, McKenna Robinson, Greg J. Marchand   +7 more
doaj   +1 more source

Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]

, 2016
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio, Argento, Giuseppe, Campanella, L, Cunsolo, G, DI STEFANO, Domenica, Lombardi, Augusto, Maggi, Stefano, Mastrangeli, Mr, Mattei, Ms, Stanzani, G, Vitale, Valeria   +10 more
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Author Correction: Laparoscopic uterine graft procurement and surgical autotransplantation in ovine model

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Francisco Miguel Sánchez-Margallo, Belén Moreno-Naranjo, María del Mar Pérez-López, Elena Abellán, José Antonio Domínguez-Arroyo, José Mijares, Ignacio Santiago Álvarez   +6 more
doaj   +1 more source

Robotic total gastrectomy with intracorporeal robot-sewn anastomosis. A novel approach adopting the double-loop reconstruction method [PDF]

, 2015
Gastric cancer constitutes a major health problem. Robotic surgery has been progressively developed in this field. Although the feasibility of robotic procedures has been demonstrated, there are unresolved aspects being debated, including the ...
Cirocchi, Roberto, Corsi, Alessia, D'ANDREA, Vito, De Santis, Francesco, DESIDERIO, JACOPO, Gemini, Alessandro, Grassi, Veronica, Parisi, Amilcare, Petrina, Adolfo, PIRONI, Daniele, Renzi, Claudio, Ricci, Francesco, SANTORO, Alberto, Trastulli, Stefano   +13 more
core   +2 more sources