When Air Leaks Meet Innovation: Obturator-Assisted Non-invasive Ventilation in a Preterm Infant With a Unilateral Cleft Lip and Palate. [PDF]
Michienzi M +3 more
europepmc +1 more source
MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio +4 more
wiley +1 more source
Effects of Intubation Duration on Trachea: A Histopathological Study
This study evaluated the histopathological effects of prolonged endotracheal intubation on the human trachea using biopsy specimens obtained during tracheotomy. Prolonged intubation was associated with progressive inflammatory and structural changes, with tracheal dilatation and perichondritis increasing significantly after 14 days.
Osman Kilic +6 more
wiley +1 more source
Social media activities to enhance the visibility of long-term invasive ventilation: A content and visibility analysis from the PRiVENT study. [PDF]
Trudzinski FC +19 more
europepmc +1 more source
A Scoping Review of Laryngeal Edema Rating Scales for Extubated Acute Respiratory Failure Survivors
This scoping review identified existing laryngeal edema rating scales and evaluated whether any are adequately designed for post‐extubation acute respiratory failure (ARF) survivors. Across 35 included studies, most used subjective binary classifications and only the RTOG and Patterson Edema scales had operational definitions and reliability/validity ...
Lalita Sabat +4 more
wiley +1 more source
Aerosol Delivery With a Vibrating Mesh Nebulizer Across Tidal Volume-Based Pediatric Invasive Ventilation Models: An In Vitro Evaluation. [PDF]
Miura S +4 more
europepmc +1 more source
Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz +7 more
wiley +1 more source
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
Efficacy of Non-invasive Ventilation Compared to Intubation in Pediatric Acute Respiratory Failure: A Meta-Analysis. [PDF]
Sajid M +9 more
europepmc +1 more source

