Results 191 to 200 of about 1,078,244 (286)

When serious becomes critical

open access: yes
Journal of Hospital Medicine, EarlyView.
Yohei Masuda
wiley   +1 more source

MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report

open access: yesThe Laryngoscope, EarlyView.
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio   +4 more
wiley   +1 more source

Effects of Intubation Duration on Trachea: A Histopathological Study

open access: yesThe Laryngoscope, EarlyView.
This study evaluated the histopathological effects of prolonged endotracheal intubation on the human trachea using biopsy specimens obtained during tracheotomy. Prolonged intubation was associated with progressive inflammatory and structural changes, with tracheal dilatation and perichondritis increasing significantly after 14 days.
Osman Kilic   +6 more
wiley   +1 more source

Social media activities to enhance the visibility of long-term invasive ventilation: A content and visibility analysis from the PRiVENT study. [PDF]

open access: yesPLoS One
Trudzinski FC   +19 more
europepmc   +1 more source

A Scoping Review of Laryngeal Edema Rating Scales for Extubated Acute Respiratory Failure Survivors

open access: yesThe Laryngoscope, EarlyView.
This scoping review identified existing laryngeal edema rating scales and evaluated whether any are adequately designed for post‐extubation acute respiratory failure (ARF) survivors. Across 35 included studies, most used subjective binary classifications and only the RTOG and Patterson Edema scales had operational definitions and reliability/validity ...
Lalita Sabat   +4 more
wiley   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

open access: yesThe Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz   +7 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

open access: yesMed Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu   +9 more
wiley   +1 more source

Efficacy of Non-invasive Ventilation Compared to Intubation in Pediatric Acute Respiratory Failure: A Meta-Analysis. [PDF]

open access: yesCureus
Sajid M   +9 more
europepmc   +1 more source

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