Results 81 to 90 of about 1,078,244 (286)

Less usual ventilatory modes: Mandatory Minute Ventilation and Adaptive Minute Ventilation

open access: yes
Weaning or liberation from mechanical ventilation is an important goal for critical care patients and in many cases this process spends most of the time in intensive care units.
Jamille Pasco, Victor Perez
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Anion–π Interaction‐Regulated Ion Generation and High Piezoionic Response in Ultrasoft Low‐Salinity Hydrogels

open access: yesAngewandte Chemie, EarlyView.
The first hydrogel system employing anion–π interactions as a central design motif is developed. The cooperative aromatic–phosphate interaction motif provides dynamic cohesion and is proposed to regulate the separation and transport of water‐derived ionic species, achieving high piezoionic response in injectable, self‐healing, ultrasoft, low‐salinity ...
Jinyang Jiang   +11 more
wiley   +2 more sources

Shrinking the room for invasive ventilation in hypercapnic respiratory failure

open access: yes, 2013
Paolo Scarpazza,1 Cristoforo Incorvaia,2 Chiara Melacini,1 Roberta Cattaneo,1 Cristiano Bonacina,1 Gian Galeazzo Riario-Sforza,2 Walter Casali1 1Pneumology Unit, Ospedale Civile, Vimercate, 2Pulmonary Rehabilitation, Istituti Clinici di Perfezionamento ...
Cattaneo R   +6 more
core  

Modafinil: a novel alternative to non-invasive ventilation in hypercapnic respiratory failure? [PDF]

open access: yes, 2015
Paulo Matos,1 Antonio M Esquinas2 1Pneumology Department, Hospitais da Universidade de Coimbra, Coimbra, Portugal; 2Intensive Care Unit, Hospital Morales Meseguer, Murcia, SpainNowadays non-invasive ventilation (NIV) is a common therapeutic option in ...
Matos P, Esquinas AM
core  

Non-invasive ventilation in chronic obstructive pulmonary disease

open access: yes, 2010
Advanced chronic obstructive pulmonary disease (COPD) is associated with peripheral and respiratory muscular weakness with nocturnal and daytime arterial blood gas abnormalities (including hypercapnia) leading to chronic respiratory failure (CRF).
Clini E. M., Ambrosino N., Crisafulli E.
core   +1 more source

Course of invasive ventilation.

open access: yes, 2022
Course of invasive ventilation.
Tobias Weiglein (13047506)   +11 more
core   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease [PDF]

open access: yes, 2006
Title: Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease. Purpose: This study examined the effects of a non-invasive ventilator on submaximal and maximal exercise performance in ...
Doggett, Anita
core   +2 more sources

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

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