Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
V. An account of a new machine, called the marine surveyor, contrived for the mensuration of the way of a ship in the sea, more correctly than by the log, or any other method hitherto used for that purpose; together with several testimonials, setting forth the usefulness of this invention [PDF]
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Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma+10 more
wiley +1 more source
A brief scientific essay on the history of invention of the main metallurgical technologies of artisan and industrial production of various metals and alloys is presented.
M.I. Baranov
doaj
XXVI. A letter from Mr. James Short, F. R. S. to the right honourable the Earl of Macclesfield, President, concering a paper of the late Servington Savery, Esq; relating to his invention of a new micrometer [PDF]
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The Centenary of James B. Neilson's Invention of Hot-Blast in Iron Smelting [PDF]
William Arthur Bone
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Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó+7 more
wiley +1 more source
Collective invention during the British Industrial Revolution: the case of the Cornish pumping engine [PDF]
pump enigine, industrial revolution, collective ...
Nuvolari, A.
core
Re-inventing inventiveness in science
openaire +4 more sources