Results 191 to 200 of about 2,239,775 (376)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Navigating the USPTO's AI inventorship guidance in AI-driven drug discovery. [PDF]

J Law Biosci
Wang J.
europepmc   +1 more source

LVIII. On the invention of the circular parts [PDF]

A. De Morgan
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The steam engine its invention and progressive improvement, an investigation of its principles, and its application to navigation, manufactures, and railways / by Thomas Tredgold ...

Thomas Tredgold, W. S. B. Woolhouse
openalex   +2 more sources

Instructional Design and Facilitation for Multigenerational Online Learning in Higher Education—Baby Boomers, Generation X, Millennials, and Generation Z

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley   +1 more source

The Invention of the Net [PDF]

, 1895
Kumagusu Minakata
openalex   +1 more source

Learning and Development Through the Scholarship of Teaching and Learning

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article focuses on learning that can facilitate the transition from being a scholarly teacher to becoming a scholar of teaching and learning, outlining the critical steps faculty can take to deepen their engagement with the scholarship of teaching and learning (SoTL).
Jennifer Friberg, Melanie Hamilton
wiley   +1 more source

New Therapeutic Options for Fusariosis: A Patent Review (2008-2023). [PDF]

J Fungi (Basel)
Faccin ID, Salomé TM, de Almeida de Souza GH, da Costa Xavier L, Alves IA, Lima VCF, Lucini F, Simionatto S, Rossato L.   +8 more
europepmc   +1 more source

American agricultural implements; a review of invention and development in the agricultural implement industry of the United States ...

, 1894
Robert L. Ardrey
openalex   +2 more sources