Results 151 to 160 of about 285,779 (275)

Multicentric Validation of a Complete Blood Count-Based Model for Breast Cancer Risk Stratification in Women Age 40-49 Years. [PDF]

open access: yesJCO Clin Cancer Inform
Araújo DC   +22 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Public impression of an innovative stair-climbing power wheelchair: A pilot survey

open access: yesHong Kong Physiotherapy Journal, 2015
S.L. Li, Grad. Dip. Adv. Manip. Ther   +1 more
doaj   +1 more source

Correction: A novel technology for home monitoring of lupus nephritis that tracks the pathogenic urine biomarker ALCAM. [PDF]

open access: yesFront Immunol
Lei R   +9 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Ostial vs Ampulla Techniques to Measure Virtual Valve-to-Coronary Distance in TAVR Coronary Obstruction Risk. [PDF]

open access: yesJACC Cardiovasc Interv
Halaby RN   +6 more
europepmc   +1 more source

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