Results 161 to 170 of about 1,484 (230)

A three-decade lake dataset on the Mongolian plateau tracking water area and quality dynamics (1990-2020). [PDF]

Sci Data
Guo J, Liu K, Na J, Liu G, Cao Z, Fan C, Xue B, Huang J, Song C.   +8 more
europepmc   +1 more source

Luminescence dating of coastal deposits from the Chanthaburi Plain, Thailand

Boreas, EarlyView.
The ongoing global sea‐level rise urges us to better understand the dynamics of coastal processes for predicting future changes. Sedimentary deposits reflect past coastal environments but require precise chronological data to place evidence into a temporal context.
Margarita Nuss, Sakonvan Chawchai, Savanna Kager, Smith Leknettip, Yunyi Li, Kannika Wangritthikraikul, Frank Preusser   +6 more
wiley   +1 more source

Integrating resource utilization and bioregenerative life support systems for sustainable space exploration. [PDF]

Front Microbiol
Esposito M, Tonietti L, Santomartino R, Giovannelli D, Chianese E, Rotundi A, Romano I, Poli A, Finore I, Cordone A, Di Donato P.   +10 more
europepmc   +1 more source

Afatinib Overcomes Osimertinib Resistance via Egfr V804F Mutation in a Syngeneic Egfr‐Mutant Lung Cancer Mouse Model

Cancer Science, EarlyView.
Using an immunocompetent mouse model of Egfr Ex19del‐driven lung cancer, we found that osimertinib‐resistant tumors acquired Egfr V804F, the murine counterpart of human EGFR V802F. Afatinib, but not osimertinib, suppressed phosphorylation of EGFR and overcame V804F‐mediated resistance, providing a preclinical rationale for biomarker‐guided therapy ...
Takaaki Tanaka, Masato Fujitani, Masataka Taoka, Iwao Shimomura, Sachi Okawa, Shunta Mori, Tadahiro Kuribayashi, Jun Nishimura, Tomoka Nishimura, Ayako Morita, Naofumi Hara, Kiichiro Ninomiya, Go Makimoto, Hisao Higo, Kammei Rai, Eiki Ichihara, Shuta Tomida, Katsuyuki Hotta, Yosuke Togashi, Yoshinobu Maeda, Katsuyuki Kiura, Ryohei Katayama, Kadoaki Ohashi   +22 more
wiley   +1 more source

Large-Scale Carbon Removal Will Create Public Health, Economic, and Climate Trade-Offs. [PDF]

Environ Sci Technol
Javadi P, O'Rourke P, Fuhrman J, Loughlin DH, Doney SC, Shobe W, Ferreira J, Clarens AF.   +7 more
europepmc   +1 more source

What controls forest litter decomposition? A coordinated distributed teabag experiment across ten mountains

Ecography, EarlyView.
Litter decomposition in mountainous forest ecosystems is an essential process that affects carbon and nutrient cycling. However, the contribution of litter decomposition to terrestrial ecosystems is difficult to estimate accurately because of the limited comparability of different studies and limited data on local microclimatic and non‐climatic factors.
Shiyu Ma, Shengbin Chen, Yi Ding, Zhongsheng He, Gang Hu, Jie Liu, Ya‐huang Luo, Kun Song, Yongchuan Yang, Xiaolei Huang, Meixiang Gao, Lan Liu, Bo Chen, Xianjin He, Xiaorong Lu, Bingwei Lv, Liang‐Liang Ma, Yani Meng, Zhongping Tian, Hong‐wei Zhang, Xijin Zhang, Yansong Zhang, Zhaochen Zhang, Shaopeng Li, Jian Zhang   +24 more
wiley   +1 more source

Regional variations in environmental impacts of NMC 811 production: Comparative LCA study across Visegrad countries. [PDF]

iScience
Jamatia T, Pechancová V, Paul D, Buchgeister J, Baumann M, Ersoy H, Erakca M, Saha P.   +7 more
europepmc   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Life Cycle and Local Environmental Impacts of Floating Photovoltaic (FPV) Systems. [PDF]

Environ Sci Technol
Seitz DM, Huijbregts MAJ, Kosten S, Hanssen SV.   +3 more
europepmc   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source