Results 81 to 90 of about 565,816 (301)

The Inventory Routing Problem with Priorities and Fixed Heterogeneous Fleet

Applied Sciences, 2020
This paper presents a new combinatorial optimization problem, the inventory routing problem with priorities, and a fixed heterogeneous fleet. In this problem, a particular set of customers has to be served before the rest of the customers using vehicles ...
Paulina A. Avila-Torres, Nancy M. Arratia-Martinez, Efraín Ruiz-y-Ruiz   +2 more
doaj   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Application of metaheuristic in inventory routing problems / Nur Arina Bazilah binti Aziz [PDF]

, 2013
The coordination of the inventory management and transportation is often known as the Inventory Routing Problems (IRP). The problem addressed in this study is outbound and inbound distribution network consisting of an assembly plant and many ...
Aziz, Nur Arina Bazilah
core  

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

A Generic Mathematical Model to Optimize the Integrted Production, Inventory and Distribution Decisions in Supply Chains [PDF]

The Egyptian International Journal of Engineering Sciences and Technology, 2016
Integration of decisions in supply chain management has received increasingconsideration recently. The Production-Inventory-Distribution-Routing Problem(PIDRP) is a recent and complex problem that integrates decisions on lot-sizing,inventory management ...
A Eltawil, N Mostafa
doaj   +1 more source

Heuristic Sequence Selection for Inventory Routing Problem [PDF]

Transportation Science, 2020
In this paper, an improved sequence-based selection hyper-heuristic method for the Air Liquide inventory routing problem, the subject of the ROADEF/EURO 2016 challenge, is described. The organizers of the challenge have proposed a real-world problem of inventory routing as a difficult combinatorial optimization problem.
openaire   +2 more sources

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

A Matheuristic for the Distance Constrained Inventory Routing Problem

Mathematics
This paper addresses the Distance-Constrained Inventory Routing Problem (DCIRP), a complex problem that combines inventory management and vehicle routing in a logistics context.
Víctor Manuel Valenzuela-Alcaraz, Efraín Ruiz-y-Ruiz, Alma Danisa Romero-Ocaño, Pamela Chiñas-Sánchez, Cecilia Guadalupe Mota-Gutiérrez   +4 more
doaj   +1 more source

Crystal Growth Engineering for Dendrite‐Free Zinc Metal Plating

Advanced Materials, EarlyView.
This research employed the rare‐earth ion dysprosium (Dy) to modulate aqueous zinc (Zn) metal plating. Integrated multiscale experiments and computational modeling unveiled the preferential adsorption of Dy on specific crystal facets, which activated screw dislocation‐driven Zn growth.
Guifang Zeng, Sharona Horta, Qing Sun, Malik Dilshad Khan, Maria Ibáñez, Yuhang Han, Shang Wang, Longqiu Li, Lijie Ci, Yanhong Tian, Andreu Cabot   +10 more
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source