Results 51 to 60 of about 1,953 (216)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Distress as a mediator for pain and activities of daily living in older adults with fibromyalgia
Frontiers in Medicine, 2022 IntroductionPain, distress, and activities of daily living impact the lives of those with chronic pain. This study investigated distress (depressive symptoms, anxiety) on the relationship between pain (intensity and pain interference) and activities of ...
Caitlin Gower +9 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Jurnal Akuntansi dan Auditing, 2016 This study aims to examine empirically the effect of corporate social responsibility (CSR), return on asset (ROA), inventory intensity, and size of firm to tax aggressiveness.
Luke Luke, Zulaikha Zulaikha
doaj +1 more source
WACANA EKONOMI (Jurnal Ekonomi, Bisnis dan Akuntansi)This study aims to determine the effect of Capital Intensity, Inventory Intensity, Profitability and Leverage on Tax Aggressiveness in Basic Industry and Chemical Sector Companies Listed on the Indonesia Stock Exchange (IDX) for the 2017-2021 period. The total number of research samples was 132 companies were obtained that met the requirements in this ...
Kadek Diviariesty +1 more
openaire +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Research and development intensity, inventory leanness, and firm performance
Journal of Open Innovation: Technology, Market and ComplexityThis study investigates whether a firm’s research and development (R&D) intensity influences its choice of an inventory leanness strategy and how R&D intensity and inventory leanness collectively impact its performance.
Md Reiazul Haque +2 more
doaj +1 more source
Assessment of the thirst dimension: integrative review
Revista Eletrônica de Enfermagem, 2017 Thirst is a multifactorial and subjective symptom that request multiple measuring instruments. The objective of this study was to identify the assessment dimensions of thirst and the measurement tools used.
Pamela Rafaela Martins +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Tax Avoidance: Capital and Inventory Intensity in BEI Non-Cyclicals (2019-2023)
Indonesian Interdisciplinary Journal of Sharia EconomicsThis study examines the effect of capital intensity and inventory intensity on tax avoidance in non-cyclical consumer sector companies listed on the Indonesia Stock Exchange (IDX) for the 2019-2023 period.
Syifa Nurul Ardiana, Intan Pramesti Dewi
doaj +1 more source