Advances and perspectives in animal models of human hepatitis A virus
Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li +3 more
wiley +1 more source
Detection of 85 new active subglacial lakes in Antarctica from a decade of CryoSat-2 data. [PDF]
Wilson SF +5 more
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Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo +7 more
wiley +1 more source
New formulation and valid inequalities for a periodic capacitated vehicle routing problem with multiple depots, heterogeneous fleet, and hard time-windows. [PDF]
Arenas-Vasco A +2 more
europepmc +1 more source
Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
Optimization of power grid material warehousing and supply chain distribution path planning based on improved PSO algorithm. [PDF]
Ge J +6 more
europepmc +1 more source
Quantum annealing-based route optimization for commercial AGV operating systems in large-scale logistics warehouses. [PDF]
Quang TN +12 more
europepmc +1 more source
A Bi-level optimization method for integrated warehouse design, storage location assignment, and order picking. [PDF]
Moghadam MF +3 more
europepmc +1 more source
ABSTRACT Excessive water production in mature oil fields necessitates robust shut‐off treatments, yet conventional polymer gels often fail under high‐temperature and high‐salinity conditions. This study aims to enhance gel thermal stability and mechanical strength by incorporating selenium‐doped Ag/AgO–ZnO nanocomposites synthesized via a novel green ...
Fadhil F. Sead +8 more
wiley +1 more source
Racial and ethnic disparities in access to acute stroke capabilities in California: Association with rurality and telestroke access. [PDF]
Zachrison KS +9 more
europepmc +1 more source

