Results 51 to 60 of about 4,480 (289)

Inventory Routing - A Strategic Management Accounting Perspective [PDF]

open access: yes, 2011
This dissertation develops a strategic management accounting perspective of inventory routing. The thesis studies the drivers of cost efficiency gains by identifying the role of the underlying cost structure, demand, information sharing, forecasting ...
Wagner, Michael
core  

Estudio del problema Inventory Routing Problem (IRP)

open access: yes, 2021
El problema integrado de gestión de inventarios y de enrutamiento Inventory Routing Problem (IRP), combina las actividades logísticas de diseño de redes y manejo de inventarios.
García Guevara, Jhonatan Stiven   +1 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The application of metaheuristics in network routing and inventory routing problem / Huda Zuhrah Ab Halim [PDF]

open access: yes, 2012
Metaheuristic methods are widely known as one of the most practical approaches in solving large (or very large) problems in many fields, specifically NP hard Combinatorial Problems.
Huda Zuhrah, Ab Halim
core  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Inventory Routing for Ammonia Supply in German Ports

open access: yesEnergies, 2022
Following the International Maritime Organization (IMO), in order to safeguard the realization of the Paris Agreement on climate protection, greenhouse gas (GHG) emissions have to be reduced by 50% by the year 2050.
Felix Prause   +2 more
doaj   +1 more source

Inventory routing for dynamic waste collection [PDF]

open access: yesWaste Management, 2014
We consider the problem of collecting waste from sensor equipped underground containers. These sensors enable the use of a dynamic collection policy. The problem, which is known as a reverse inventory routing problem, involves decisions regarding routing and container selection. In more dense networks, the latter becomes more important.
Mes, Martijn R.K.   +2 more
openaire   +3 more sources

Disruption management of the vehicle routing problem with vehicle breakdown [PDF]

open access: yes, 2011
This paper introduces a new class of problem, the disrupted vehicle routing problem (VRP), which deals with the disruptions that occur at the execution stage of a VRP plan.
Eglese, R W, Mu, Q, Fu, Z, Lysgaard, J
core  

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