Results 51 to 60 of about 1,120,081 (249)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Classification and Prediction of Topological Insulators by Using the Density of States

Mathematics
In order to characterize topological insulators it is customary to use representations of the electronic structure, such as the band structure, where the energy of electrons is represented as a function of their momenta.
Alejandro Díaz-Nadales, Zulima Fernández-Muñiz, Juan L. Fernández-Martínez, Víctor M. García-Suárez   +3 more
doaj   +1 more source

Prediction of Protein Tertiary Structure via Regularized Template Classification Techniques

Molecules, 2020
We discuss the use of the regularized linear discriminant analysis (LDA) as a model reduction technique combined with particle swarm optimization (PSO) in protein tertiary structure prediction, followed by structure refinement based on singular value ...
Óscar Álvarez-Machancoses, Juan Luis Fernández-Martínez, Andrzej Kloczkowski   +2 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Carleman estimate for stochastic parabolic equations and inverse stochastic parabolic problems [PDF]

, 2012
In this paper, we establish a global Carleman estimate for stochastic parabolic equations. Based on this estimate, we study two inverse problems for stochastic parabolic equations.
Lü, Q., Lü Q.
core   +1 more source

Invited review: efficient computation strategies in genomic selection

Animal, 2017
The purpose of this study is review and evaluation of computing methods used in genomic selection for animal breeding. Commonly used models include SNP BLUP with extensions (BayesA, etc), genomic BLUP (GBLUP) and single-step GBLUP (ssGBLUP). These models
I. Misztal, A. Legarra
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Some Remarks on Invertible Refined Neutrosophic Square Matrices [PDF]

Neutrosophic Sets and Systems
The main goal of this article is to define the adjoint of refined (resp., n-refined) neutrosophic square matrices, and to study the inverse of these matrices in terms of refined (resp., n-refined) neutrosophic determinants and adjoints. Also, it presents
Ahmad A. Abubaker, Abdallah Shihadeh, Mayada Abualhomos, Khaled Matarneh, Mutaz Shatnawi, Ahmed Atallah Alsaraireh, P. Prabakaran, Abdallah Al-Husban   +7 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Symmetric Tridiagonal Inverse Quadratic Eigenvalue Problems with Partial Eigendata [PDF]

, 2007
In this paper we concern the inverse problem of constructing the n-by-n real symmetric tridiagonal matrices C and K so that the monic quadratic pencil Q(¸) := ¸2I + ¸C + K (where I is the identity matrix) possesses the given partial eigendata.
白正简, Zheng-Jian Bai
core