Results 41 to 50 of about 33,194 (158)

Interval-cohort designs and bias in the estimation of per-protocol effects: a simulation study

Trials, 2019
Background Randomized trials are considered the gold standard for making inferences about the causal effects of treatments. However, when protocol deviations occur, the baseline randomization of the trial is no longer sufficient to ensure unbiased ...
Jessica G. Young, Rajet Vatsa, Eleanor J. Murray, Miguel A. Hernán   +3 more
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Pragmatic trials: ignoring a mediator and adjusting for confounding

BMC Research Notes, 2019
Objectives In pragmatic trials, the new treatment is compared with usual care (heterogeneous control arm) that makes the comparison of the new treatment with each treatment within the control arm more difficult.
Paraskevi Pericleous
doaj   +1 more source

Dexmedetomidine shortens time to extubation in mechanically ventilated ICU patients: A retrospective cohort study

陆军军医大学学报
Objective To investigate the impact of different sedation strategies on short-term outcomes in intensive care unit (ICU) patients receiving invasive mechanical ventilation (IMV), and to assess whether these effects differ in special populations such as ...
SUN Jing, LI Yujie
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Impact of age on the outcomes of extracorporeal cardiopulmonary resuscitation: analysis using inverse probability of treatment weighting

European Journal of Cardio-Thoracic Surgery, 2021
Abstract OBJECTIVESPatient selection is crucial to improving the outcomes of extracorporeal cardiopulmonary resuscitation (ECPR). However, ECPR’s efficacy with older patients remains unknown.METHODSWe reviewed patients who underwent extracorporeal membrane oxygenation (ECMO) for refractory cardiac arrest from January 2006 to December 2018.
Young Su Kim, Yang Hyun Cho, Jeong Hoon Yang, Ji-Hyuk Yang, Suryeun Chung, Gee Young Suh, Kiick Sung   +6 more
openaire   +2 more sources

Maintaining long-term frequent tea consumption could reduce the risk of cognitive decline: results from a 10-year longitudinal study

Frontiers in Nutrition
BackgroundPrevious studies have suggested that tea may have neuroprotective effect. This study aimed to investigate the association between tea consumption frequency and cognitive decline, taking into account changes in consumption habits and selection ...
Jie Huang, Jie Huang, Hongfen Wang, Yuying Wang, Yuying Wang, Jiaqi Xu, Jiaqi Xu, Jiameng Ni, Jiameng Ni, Mengjie Li, Mengjie Li, Bin Chen, Zaixiang Tang, Zaixiang Tang, Yu Zhang, Liping Tan   +15 more
doaj   +1 more source

Effectiveness of fluoroquinolone antimicrobials in addition to tetracyclines for Japanese spotted fever: A retrospective analysis using a national inpatient database

International Journal of Infectious Diseases, 2022
Objectives: This study aim to evaluate the effectiveness of fluoroquinolone (FQ) antimicrobial therapy in combination with tetracyclines (TCs) in patients with Japanese spotted fever (JSF) using a nationwide inpatient database in Japan.Methods: We ...
Satoshi Kutsuna, Hiroyuki Ohbe, Hiroki Matsui, Hideo Yasunaga   +3 more
doaj   +1 more source

On flexible inverse probability of treatment and intensity weighting: Informative censoring, variable selection, and weight trimming

Statistical Methods in Medical Research
Many observational studies feature irregular longitudinal data, where the observation times are not common across individuals in the study. Furthermore, the observation times may be related to the longitudinal outcome. In this setting, failing to account for the informative observation process may result in biased causal estimates.
Grace Tompkins, Joel A Dubin, Michael Wallace   +2 more
openaire   +3 more sources

Effect of Fluoroscopy‐Only Versus Transesophageal Echocardiography/Intracardiac Echocardiography Guidance in Left Atrial Appendage Occlusion on Stroke Prevention: Analysis From the RECORD I Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence regarding the link between imaging modality and stroke prevention outcomes of left atrial appendage occlusion is currently lacking.
Ping Wang, Zhengquan Chen, Yongmeng Yan, Guotao Fu, Jianzheng Liu, Ruining Zhang, Zhongbao Ruan, Xianxian Zhao, Haixiong Wang, Baopeng Tang, Xuegang Xie, Fu Yi, Yuan Bai, Xianhui Zhou, Junguo Zhu, Hongde Hu, Scot Garg, Patrick W. Serruys, Chao Gao, Ling Tao   +19 more
doaj   +1 more source

Metformin Reduces the Risk of Diverticula of Intestine in Taiwanese Patients with Type 2 Diabetes Mellitus

Frontiers in Pharmacology, 2021
Aim: To investigate the risk of diverticula of intestine associated with metformin use.Methods: This retrospective cohort study used the Taiwan’s National Health Insurance database to enroll 307,548 ever users and 18,839 never users of metformin.
Chin-Hsiao Tseng, Chin-Hsiao Tseng, Chin-Hsiao Tseng   +2 more
doaj   +1 more source

Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The optimal antiplatelet regimen after standard endovascular aneurysm repair (EVAR) in patients without atherosclerotic cardiovascular disease remains uncertain.
Ki Hong Choi, Danbee Kang, Jihee Nam, Take Kyu Park, Myung Gyu Song, Tae‐Seok Seo, Woo Jin Yang, Seung‐Hyuk Choi   +7 more
doaj   +1 more source