Results 51 to 60 of about 5,943,425 (299)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Inverse of the string theory KLT kernel
Journal of High Energy Physics, 2017 The field theory Kawai-Lewellen-Tye (KLT) kernel, which relates scattering amplitudes of gravitons and gluons, turns out to be the inverse of a matrix whose components are bi-adjoint scalar partial amplitudes.
Sebastian Mizera
doaj +1 more source
Review of seismic inverse scattering migration and inversion
地球与行星物理论评, 2021 With the shifting toward deeper, geologically more complex, and more subtle hydrocarbon reservoirs than before, the exploration of oil and gas resources is becoming more and more difficult.
Weijian Mao, Wuqun Li, Wei Ouyang
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Creep theory inverse problem for non-work-hardening body
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014 The body formation by constant external forces in the conditions of the steady-state creep during set time problem is formulated and solved so that after removal of loadings the movements of points of a surface accepted preset values.
Igor Yu Tsvelodub
doaj +1 more source
Inverse scattering problem in turbulent magnetic fluctuations [PDF]
Annales Geophysicae, 2016 We apply a particular form of the inverse scattering theory to turbulent magnetic fluctuations in a plasma. In the present note we develop the theory, formulate the magnetic fluctuation problem in terms of its electrodynamic turbulent response ...
R. A. Treumann +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Inverse medium problem for a singular contrast [PDF]
, 2019 We consider an inverse medium problem in two- and three-dimensional cases. Namely, we investigate the problem of reconstruction of unknown compactly supported refractive index (contrast) from L-2 with a fixed positive wave number.
T. Tyni, Serov, V., Tyni, T., V. Serov
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source