Results 51 to 60 of about 12,345,570 (252)

¿Ley de inversión social o reforma tributaria?

open access: yesApuntes del CENES, 2022
La ley 2155 de 2021 sancionada por el presidente de la República el 14 de septiembre del año anterior es la última reforma tributaria de las cuatro que presentó en su gobierno. La primera, la tumbó la corte constitucional por vicios de forma; la segunda,
Luis Eudoro Vallejo Zamudio
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Rentabilidad de la educación en Bogotá

open access: yesRevista Colombiana de Educación, 1979
Identificar y clasificar oportunidades rentables de inversión es tarea empírica importante, aunque a veces difícil de la ciencia económica. Formular guías para la asignación de recursos de inversión pública exige información sobre la rentabilidad tanto ...
P. Schultz
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Estudio de caso sobre la inversión social en Bogotá

open access: yesRevista Estudios Socio-Jurídicos, 2010
El enunciado constitucional del Estado Social de Derecho implica el adelantamiento de acciones administrativas en pro de su efectiva concreción. En ese sentido, una herramienta la constituyen los planes de desarrollo, tanto en el ámbito nacional como en ...
Manuel Alberto Restrepo-Medina
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Propuesta metodológica de formulación de proyectos de inversión social para implementar en el SENA [PDF]

open access: yes, 2019
100 páginas y anexosOur work shows the diagnosis, methodological development and the implementation of a methodology for the formulation of social investment projects, which should serve as a base input for the structuring and subsequent implementation ...
Blanco Santillana, Claudia Liliana   +1 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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