Results 81 to 90 of about 22,422,719 (302)
Smoothed Analysis of Moore–Penrose Inversion [PDF]
SIAM Journal on Matrix Analysis and Applications, 2010 We perform a smoothed analysis of the condition number of rectangular matrices. We prove that, asymptotically, the expected value of this condition number depends only on the elongation of the matrix and not on the center and variance of the underlying probability distribution.
Peter Bürgisser, Felipe Cucker
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Inverse image analysis generalises strictness analysis
Information and Computation, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
New magnetic inversion scheme including terrain-effect correction
Earth, Planets and SpaceMagnetic inversion analysis is used to estimate the subsurface magnetization structure from surface magnetic anomalies and plays a key role in geophysical exploration due to its sensitivity to lithological variations.
Ryosuke Ito, Mitsuru Utsugi
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Multidimensional inverse-scattering and clifford analysis
Applied Mathematics Letters, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
A Deep Neural Network for Acoustic-Articulatory Speech Inversion [PDF]
, 2011 In this work, we implement a deep belief network for the acoustic-articulatory inversion mapping problem. We find that adding up to 3 hidden-layers improves inversion accuracy.
Renals, S. +2 more
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