SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio +6 more
wiley +1 more source
Unraveling the symmetry of Al<sub>5</sub>C<sub>3</sub>N. [PDF]
Shtender V +8 more
europepmc +1 more source
On the inversion formula for the characteristic function [PDF]
openaire +3 more sources
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim +9 more
wiley +1 more source
Prevalence and Sex-Specific Distribution of Electrocardiographic Variants in Normotensive Nigerian University Students: A Cross-Sectional Study. [PDF]
Egharevba JE +6 more
europepmc +1 more source
An exciting Approach to Theoretical Spectroscopy
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno +29 more
wiley +1 more source
Calibration, Sensitivity and Uncertainty Analysis of Complex Ecological Models-A Review. [PDF]
Malchow AK, Hartig F.
europepmc +1 more source
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
Correction: Nakajima et al. Pretreatment Prognostic Factors for Intradiscal Condoliase Injection in Patients with Lumbar Disc Herniation: Insights from Clinical and MRI-Based Quantitative Analysis. <i>J. Clin. Med.</i> 2025, <i>14</i>, 1509. [PDF]
Nakajima H +5 more
europepmc +1 more source
Physics‐Informed Neural Network‐Enabled Forward Prediction and Inverse Design of Ring Origami
This work presents a KRT‐PINN framework that integrates Kirchhoff rod theory with physics‐informed neural networks for the forward prediction and inverse design of ring origami consisting of closed‐loop rods. The framework predicts stable states of segmented rings with prescribed natural‐curvature profiles and determines the natural‐curvature profiles ...
Luyuan Ning +3 more
wiley +1 more source

