Results 61 to 70 of about 10,032 (266)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Este artigo apresenta a modelagem e o controle de um microinversor monofásico em ponte completa com transformador de alta frequência que pode ser utilizado como parte de um inversor de dois estágios de conversão sem transformador no estágio CC-CC, ou ...
J. R. Gazoli +4 more
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
La búsqueda de fuentes de energía que ayuden a soportan los crecientes requerimientos energéticos sin sacrificar el medio ambiente es un punto importante dentro del desarrollo de las naciones.
José Maestre, Gerzhel Gómez Julio
doaj
Modulação Descontínua para Conversor de Capacitor Flutuante com Controle de Tensão dos Capacitores
Este artigo apresenta uma estratégia de modulação descontínua baseada em portadoras para um inversor de capacitores flutuantes de três níveis. Esta modulação é capaz de equilibrar as tensões dos capacitores flutuantes por meio de um controlador em malha
Mauricio M. da Silva +2 more
doaj +1 more source
Este trabalho apresenta o desenvolvimento de um inversor monofásico isolado conectado à rede empregando a topologia boost-full-bridge (BFB). Utiliza-se este conversor CC-CC em uma estrutura unfolding na qual se modula semiciclos positivos senoidais de ...
Julio Cesar Moura Fae +5 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Inversor cuasi-cuadrado trifásico [PDF]
Comprende el diseño, construcción y análisis de un inversor trifásico con frecuencia variable en un rango de 0 a 100 Hz, utilizando elementos de última tecnología, como son los transistores de compuerta aislada, IGBTs con sus respectivos drivers.
Silva Monteros, Franklin Manuel
core

