Results 251 to 260 of about 247,576 (315)

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

Advanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng   +16 more
wiley   +1 more source

The Complete Chloroplast Genome of <i>Idesia polycarpa</i> and Comparative Analysis of Related Species. [PDF]

Genes (Basel)
Fu X, Luo J, Guo Y, Feng D, Deng Y, Kuang M, Zhou H, Liu X, Sun C.   +8 more
europepmc   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

The complete chloroplast genome of <i>Stachyurus himalaicus</i>. [PDF]

Mitochondrial DNA B Resour
Chen Y, Li R, Wang S, Xiong S, Huang Y.
europepmc   +1 more source

Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications

Advanced Science, EarlyView.
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley   +1 more source

Comparative Genomics and Phylogenetic Analyses of <i>Aquarius macrophyllus</i> and Related Genera in Alismataceae Based on Plastome Data. [PDF]

Ecol Evol
Li J, Wei S, Ying J, Lu Q.
europepmc   +1 more source

A Comparative Analysis of Whole Plastid Genomes from the Apiales: Expansion and Contraction of the Inverted Repeat, Mitochondrial to Plastid Transfer of DNA, and Identification of Highly Divergent Noncoding Regions

, 2015
S. R. Downie, R. Jansen
semanticscholar   +1 more source

DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication

Journal of Virology, 1994
S. Holt, G. Schuller, V. Wilson
semanticscholar   +1 more source

Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet

Advanced Science, EarlyView.
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang, Lianhuang Li, Janet E. Sorrells, Jianxin Chen, Haohua Tu   +4 more
wiley   +1 more source

The complete chloroplast genome and phylogenetic analysis of <i>Cyananthus macrocalyx</i> Franch. 1887 Campanulaceae. [PDF]

Mitochondrial DNA B Resour
Ma HT, Lei D, Chen QY, Jiang B, Zhang YZ.   +4 more
europepmc   +1 more source