Results 21 to 30 of about 138,993 (305)

Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism

open access: yesNature Communications, 2023
Inverted duplications, also known as foldback inversions, are commonly observed in cancers and are the major class of chromosome rearrangement recovered from yeast cells lacking Mre11 nuclease activity. Foldback priming at DNA double-strand breaks (DSBs)
Amr M. Al-Zain   +3 more
doaj   +1 more source

Rapid identification and differentiation of the vaccine strain Rac H from EHV 1 field isolates using a non-radioactive DNA probe [PDF]

open access: yes, 1992
A method for rapid differentiation between the EHV 1 live vaccine strain Rac H and field isolates is described. Total DNA was isolated from virus-infected small scale cell cultures.
Eichhorn, Werner   +3 more
core   +1 more source

Single-cell copy number variant detection reveals the dynamics and diversity of adaptation.

open access: yesPLoS Biology, 2018
Copy number variants (CNVs) are a pervasive source of genetic variation and evolutionary potential, but the dynamics and diversity of CNVs within evolving populations remain unclear.
Stephanie Lauer   +6 more
doaj   +1 more source

Target site recognition by a diversity-generating retroelement. [PDF]

open access: yesPLoS Genetics, 2011
Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes.
Huatao Guo   +7 more
doaj   +1 more source

Comparative Analysis of Complete Chloroplast Genomes of 13 Species in Epilobium, Circaea, and Chamaenerion and Insights Into Phylogenetic Relationships of Onagraceae

open access: yesFrontiers in Genetics, 2021
The evening primrose family, Onagraceae, is a well defined family of the order Myrtales, comprising 22 genera widely distributed from boreal to tropical areas.
Yike Luo   +9 more
doaj   +1 more source

Next generation sequencing reveals the complete plastome sequence of newly discovered cliff-dwelling Sonchus boulosii (Asteraceae: Cichorieae) in Morocco [PDF]

open access: yes, 2019
The complete chloroplast genome sequences of newly discovered cliff-dwelling species of Sonchus, S. boulosii, were reported in this study. The S. boulosii plastome was 152,016 bp long, with the large single copy (LSC) region of 83,988 bp, the small ...
Kim, Seon-Hee   +2 more
core   +1 more source

Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs

open access: yeseLife, 2020
Previously, we identified long repeat sequences that are frequently associated with genome rearrangements, including copy number variation (CNV), in many diverse isolates of the human fungal pathogen Candida albicans (Todd et al., 2019).
Robert T Todd, Anna Selmecki
doaj   +1 more source

Investigating the DNA-Binding Site for VirB, a Key Transcriptional Regulator of Shigella Virulence Genes, Using an In Vivo Binding Tool [PDF]

open access: yes, 2019
The transcriptional anti-silencing and DNA-binding protein, VirB, is essential for the virulence of Shigella species and, yet, sequences required for VirB-DNA binding are poorly understood.
Karabachev, Alexander D.   +6 more
core   +2 more sources

Complete chloroplast genome of Sinosenecio jishouensis D.G. Zhang, Ying Liu & Q. E. Yang (Asteraceae), a narrow endemic species in Wuling Mountain Region, China

open access: yesMitochondrial DNA. Part B. Resources, 2021
The first complete chloroplast genome (cp) of Sinosenecio jishouensis D.G. Zhang, Ying Liu & Q. E. Yang (Asteraceae) was sequenced and assembled in this study. The cp genome was 151,257 bp in length, including a large single-copy(LSC) region of 83,373 bp,
Qiang Zhou   +4 more
doaj   +1 more source

The complete chloroplast genomes of two Pedicularis species (Orobanchaceae) from Southwest China

open access: yesMitochondrial DNA. Part B. Resources, 2022
We report the complete chloroplast genome (plastome) sequences of Pedicularis cephalantha (147,087 bp) and P. nigra (145,726 bp), endemic to southwestern China.
Wei-Jia Wang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy