Results 201 to 210 of about 3,638 (262)

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Tri-Acceptor Skeleton Balancing Ambipolar Mixed Ionic-Electronic Transport in Organic Conductors. [PDF]

open access: yesAngew Chem Int Ed Engl
Zhao J   +9 more
europepmc   +1 more source

Dynamics of genetic circuits in Pseudomonas protegens.

open access: yesCell Syst
Rico J   +3 more
europepmc   +1 more source

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