Results 41 to 50 of about 44,590 (284)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Development of df/dt function in inverters for synthetic inertia

open access: yesEnergy Reports, 2023
The increasing share of renewable energy-based resources in the power grid has a detrimental impact on the power system stability. As these resources are inverter-based, they decrease the overall inertia of the grid.
Jun Hashimoto   +12 more
doaj   +1 more source

IPMSM torque control strategies based on LUTs and VCT feedback for robust control under machine parameter variations [PDF]

open access: yes, 2016
In recent years, Interior Permanent Magnet Synchronous Machines (IPMSMs) have attracted a considerable attention in the scientific community and industry for Electric and Hybrid Electric Vehicle (HEV) propulsion systems.
Arias Pujol, Antoni   +6 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A simple maximum power point tracking based control strategy applied to a variable speed squirrel cage induction generator [PDF]

open access: yes, 2012
This paper presents a comprehensive modelling and control study of a variable speed wind energy conversion system based on a squirrel-cage induction generator (SCIG).
Allali, A.   +4 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Impact of Inverter Controls in Small-Signal Stability of Power Systems Dominated by Inverter-Based Resources

open access: yesIEEE Access
Initiatives to decarbonize contemporary power systems will lead to power systems dominated by inverter-based resources (IBR). These IBRs are broadly classified into grid-following (GFL) and grid-forming (GFM) inverter control regimes.
Xian Gao   +8 more
doaj   +1 more source

Energy Production Analysis and Optimization of Mini-Grid in Remote Areas: The Case Study of Habaswein, Kenya [PDF]

open access: yes, 2017
Rural electrification in remote areas of developing countries has several challenges which hinder energy access to the population. For instance, the extension of the national grid to provide electricity in these areas is largely not viable.
DEL CITTO, Riccardo   +8 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Overview of three-phase inverter topologies for distributed generation purposes [PDF]

open access: yes, 2010
The increasing presence of single-phase distributed generators and unbalanced loads in the electric power system may lead to unbalance of the three phase voltages, resulting in increased losses and heating.
De Kooning, Jeroen   +5 more
core   +1 more source

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