Results 71 to 80 of about 1,494 (268)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Full column rank preservers that preserve semipositivity of matrices
Special Matrices, 2018 Left invertibility preservers on Mm,n(ℝ), m ≥ n, that preserve either semipositivity of matrices or the subset of minimally semipositive matrices are studied. We prove that such maps cannot be degenerate.
Arumugasamy Chandrashekaran +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
A Unified Framework for Fractional and Non-Fractional Operators in Some Function Spaces
Fractal and FractionalThis paper examines a family of operators that combine the features of fractional-order and classical operators. Our goal is to obtain results on their invertibility in function spaces, based on their inherent improving properties.
Mieczysław Cichoń +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
On Invertibility of Large Binary Matrices
MathematicsMany data processing applications involve binary matrices for storing digital information. At present, there are limited results in the literature about algorithms for inverting large binary matrices.
Ibrahim Mammadov +2 more
doaj +1 more source
Connections between the stability of a Poincare map and boundedness of certain associate sequences
Electronic Journal of Qualitative Theory of Differential Equations, 2011 Let $m\ge 1$ and $N\ge 2$ be two natural numbers and let ${\mathcal{U}}=\{U(p, q)\}_{p\ge q\ge 0}$ be the $N$-periodic discrete evolution family of $m\times m$ matrices, having complex scalars as entries, generated by ${\mathcal{L}}(\mathbb{C}^m ...
Sadia Arshad +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source