Results 141 to 150 of about 2,610,164 (335)

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Investigate Invertibility of Sparse Symmetric Matrix

open access: yes, 2017
In this paper, we investigate the invertibility of sparse symmetric matrices. We show that for an $n\times n$ sparse symmetric random matrix $A$ with $A_{ij} = _{ij} _{ij}$ is invertible with high probability. Here, $ _{ij}$s, $i\ge j$ are i.i.d. Bernoulli random variables with $\mathbb{P} \left( _{ij}=1 \right) =p \ge n^{-c}$, $ _{ij}, i\ge j ...
openaire   +2 more sources

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa   +5 more
wiley   +1 more source

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee   +10 more
wiley   +1 more source

INVERTIBILITY OF SUBMATRICES OF THE PASCAL MATRIX AND BIRKHOFF INTERPOLATION

open access: yesJournal of Mathematical Sciences: Advances and Applications, 2016
The infinite upper triangular Pascal matrix is T = [( j )i] for 0 ≤ i, j. It is easy to see that any leading principle square submatrix is triangular with determinant 1, hence invertible. In this paper, we investigate the invertibility of arbitrary square submatrices Tr, c comprised of rows r = [r0, … , rm ] and columns c = c0 , … , cm[] of T. We
openaire   +3 more sources

Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting

open access: yesAdvanced Healthcare Materials, EarlyView.
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari   +9 more
wiley   +1 more source

Generating Self-Invertible Matrices by Hill Cipher Algorithm In Gaussian Integers

open access: yesAcademic Science Journal
In this paper, the Creating self-reflexive matrices for the Hill Cipher algorithm in Gaussian integers is discussed. It's not always possible to find the inverse of the matrix that was used to encrypt the plaintext.
Ayat A. Jafaar, Rifaat Z. Khalaf
doaj   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang   +9 more
wiley   +1 more source

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