Results 201 to 210 of about 5,939 (303)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis   +19 more
wiley   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin   +5 more
wiley   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

open access: yesAdvanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier   +2 more
wiley   +1 more source

Customizable Fabrication of 2D and Conformal Multielectrode Arrays for 3D Printed Organotypic Bioelectronic Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Aerosol jet printing enables rapid, customizable fabrication of flexible, fully gold multi‐electrode arrays (MEAs) for organotypic bioelectronic interfaces. The printed MEAs exhibit stable electrochemical performance, cytocompatibility, and functionality in recording and stimulation, including integration with 3D‐printed constructs.
Ernest Cheah   +7 more
wiley   +1 more source

3D Printing Strategies for Bioengineering Human Cornea

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan   +4 more
wiley   +1 more source

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