Results 41 to 50 of about 5,577 (256)
Restricted invertibility of continuous matrix functions
Operators and Matrices, 2022 23 ...
Fan, Adrian +6 more
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
DIAGONALISASI MATRIKS UNTUK MENYELESAIKAN MODEL MANGSA-PEMANGSA
Barekeng, 2007 Diagonalization of a square matrix A is based on the process of finding an invertible matrix P such that , where D is diagonal matrix. Matrix P is construct of eigenvectors which corresponding to every eigenvalue of A.
Elvinus R. Persulessy
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Combined matrix of diagonally equipotent matrices
Special Matrices, 2023 Let C(A)=A∘A−T{\mathcal{C}}\left(A)=A\circ {A}^{-T} be the combined matrix of an invertible matrix AA, where ∘\circ means the Hadamard product of matrices.
Bru Rafael +4 more
doaj +1 more source
From Fractal Behavior of Iteration Methods to an Efficient Solver for the Sign of a Matrix
Fractal and Fractional, 2022 Investigating the fractal behavior of iteration methods on special polynomials can help to find iterative methods with global convergence for finding special matrix functions.
Tao Liu +3 more
doaj +1 more source
A Method for Inverting the Channel Matrix in R-Matrix Theory [PDF]
Australian Journal of Physics, 1972 A technique is presented for inverting the channel matrix which occurs in R-matrix theory. The collision matrix is expressed in a form which does not involve matrix inversions; it is evaluated by the application of a recurrence relation. The connection between this method and the level matrix formalism is examined.
openaire +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source