Results 151 to 160 of about 23,565,951 (358)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Mapping Mutual Fund Investor Characteristics and Modeling Switching Behavior [PDF]
Securing a mutual fund that meets investment goals is an important reason why some investors exclusively stay with a particular mutual fund and others switch funds within their fund family.
Akhter, Syed H. +2 more
core +1 more source
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
Sovereign debt buybacks as a signal of creditworthiness [PDF]
To solve the puzzle of attitudes toward debt buybacks, the authors use a model that combines considerations of debt overhang with the possibility of asymmetrical information between debtor countries and their creditors.
Acharya, Sankarshan, Diwan, Ishac
core
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rates (ASYRs) for site‐specific OA across 204 countries and territories were obtained from the Global Burden of Diseases, Injuries, and ...
Haowei Chen +14 more
wiley +1 more source
Spatial Competition, Sequential Entry, and Technology choice [PDF]
This article introduces technology choice into a Hotelling model of spatial competition. This yields two entry deterrence devices, as well as complex strategic choices for the firms and a rich of industry structure.
Georg Götz
core
Objective This study aimed to determine if program format (in‐person, virtual, or hybrid) results in differences in 3‐month outcomes of pain, function, quality of life, self‐efficacy, and chair stands in a hip/knee osteoarthritis‐management program. Methods A secondary analysis of the Good Life with osteoArthritis in Denmark (GLA:D) Canada database was
Jill Van Damme +7 more
wiley +1 more source
Spatial patterns of ecosystem services and their determinants in small mountainous watersheds
【Objective】 This paper is to address the research gap in ecosystem services of small mountainous watersheds and provide scientific support for comprehensive management and sustainable development of such regions.
LIU Rui, FAN Tianhu, WANG Keyu, XIAO He
doaj +1 more source
A New Test of Borrowing Constraints for Education [PDF]
We discuss a simple model in which parents and children make investments in the children’s education, investments for other purposes, and parents can transfer cash to their children.
Ananth Seshadri +2 more
core

