Results 81 to 90 of about 4,865,607 (338)
Consideraciones sobre la reflexividad en el proceso de construcción de objetos de investigación biográficos [PDF]
, 2018 Fil: Lemus, Magdalena. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación. Instituto de Investigaciones en Humanidades y Ciencias Sociales (UNLP-CONICET); Argentina. ; Fil: Guevara, Bárbara. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación.
Lemus, Magdalena +2 more
openaire +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Investigación práctica en educación: investigación-acción [PDF]
, 2011 En este artículo se expone la metodología de la investigación-acción, una metodología utilizada en investigación educativa en la que el profesor investiga sobre su propia práctica docente.
Ferrández Berrueco, Reina +1 more
core
Regulation of plasma membrane expansion during axon formation [PDF]
, 2018 Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano +2 more
core +1 more source
Investigación en capacitación docente
Revista Colombiana de Educación, 1978 Como es bien conocido, el maestro desempeña un papel decisivo en el mejoramiento cualitativo de la educación, luego su capacitación debe ser uno de los pilares de cualquier programa de reforma educativa y por consiguiente, debe estar fundamentada en la ...
Grupo de Investigación Grupo de Investigación
doaj +1 more source
, 2020 This academic article seeks to answer the questions: What are the theoretical configurations assumed from the research paradigms and what are the new challenges posed around them from educational research? To do so, it starts with a theoretical review of
Sorangela Miranda Beltrán +1 more
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Islam: región MENA y métodos de investigación [PDF]
, 2019 The distinction between normative and objective knowledge and how social scientist imagine that their research is solely built on objectivity is currently being challenged especially in the political science field. If we take culture as an example and
Abdelkader, Deina
core +2 more sources
Información sobre el Círculo de Estudios Geográficos “Francisco José de Caldas”
Revista Colombiana de Educación, 2017 Un grupo de estudiantes de la Universidad Pedagógica Nacional con inquietudes investigativas ha creado el “Círculo de Estudios Geográficos Francisco José de Caldas” cuyos objetivos son: Formar equipos de investigación en diferentes áreas, tanto técnicas ...
Grupo de Investigación Grupo de Investigación
doaj +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source