Results 21 to 30 of about 25,448 (128)

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

Espiritualidad, religiosidad y enfermedad: una mirada desde mujeres con cáncer de mama

Avances en Psicología Latinoamericana, 2015
The present investigation aims to explore the role of spirituality and religiosity in the way that women with breast cancer assume, signifiy and face their illness.
Yesica Milena Puentes Silva, Sandra Carolina Urrego Barbosa, Ricardo Sánchez Pedraza   +2 more
doaj   +1 more source

Earlier strength recovery with partial‐thickness versus full‐thickness quadriceps tendon graft for anterior cruciate ligament reconstruction in competitive soccer players

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to compare strength recovery, functional and clinical outcomes between full‐ and partial‐thickness quadriceps tendon autografts for 12 months post‐operatively and to examine the clinical implications of graft thickness in anterior cruciate ligament reconstruction among non‐professional competitive soccer players ...
Jose Luis Martin‐Alguacil, Manuel Arroyo‐Morales, Maria Lopez‐Garzon, Víctor Bolívar‐Arroyo, Irene Cantarero‐Villanueva, Juan M. Fernández‐Domínguez, Jose M. Rodriguez‐Delgado   +6 more
wiley   +1 more source

Cost-effectiveness of rapid-deployment aortic valve replacement over TAVI: a real-world retrospective cohort study

Journal of Cardiothoracic Surgery
Background Aortic valve replacement (AVR) is the standard treatment for severe aortic stenosis. While transcatheter aortic valve implantation (TAVI) has recently been widely recommended, concerns remain regarding real-world long-term valve durability and
Kevin Maldonado-Cañón, Silvia Alejandra Prada Liévano, Germán Molina, Carlos Pérez Rivera, Héctor Olaya, Valentina Pérez-Ariza, Nicolás Forero, Santiago Niño, Javier Maldonado-Escalante   +8 more
doaj   +1 more source

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

Movement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson, Isaac Adanyeguh, David J. Arpin, Tetsuo Ashizawa, Benjamin Bender, Fernando Cendes, Xi Chen, Giulia Coarelli, Léo Coutinho, Andreas Deistung, Imis Dogan, Alexandra Durr, Jennifer Faber, for the ESMI MR Study Group, Juan Fernandez‐Ruiz, Mónica Ferreira, Marcondes C. França, Sophia L. Göricke, Shuo Han, Thomas Klockgether, Chen Liu, Jun Luo, Alberto R.M. Martinez, Sergio E. Ono, Chiadi U. Onyike, Gülin Öz, for the EUROSCA MR Study Group, Henry Paulson, Jerry L. Prince, Kathrin Reetz, Thiago J.R. Rezende, Matthis Synofzik, Hélio A. Ghizoni Teive, Sophia I. Thomopoulos, Paul M. Thompson, Dagmar Timmann, David Vaillancourt, Bart van de Warrenburg, Judith van Gaalen, Xingang Wang, Philipp Wegner, Sarah H. Ying, Ian H. Harding, Carlos R. Hernandez‐Castillo   +43 more
wiley   +1 more source

DNAJC13 Variants Show No Robust Association With Parkinson's Disease in a Multiancestry Cohort

Movement Disorders, EarlyView.
Abstract Background DNAJC13 was initially linked to autosomal dominant (AD) Parkinson's disease (PD) in a European Mennonite family carrying the p.N855S variant. However, imperfect segregation and conflicting reports of pathogenicity raised uncertainty of the role of DNAJC13 in the disease.
César Luis Ávila, Mariam Isayan, Yasser Mecheri, Paula Saffie‐Awad, María Milagros Leila, Laurel A. Screven, Hampton Leonard, Maria Teresa Periñan, Sheila Yeboah, Kristin Levine, Mary B. Makarious, on behalf of the Global Parkinson's Genetics Program (GP2)   +11 more
wiley   +1 more source

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo, M. Palacio, C. Rueda, M. Larroya, D. Boada, J. Ponce, M. Guilleumes, O. Gómez, S. Ferrero, E. Gratacós, F. Crispi, T. Cobo   +11 more
wiley   +1 more source

Tópicos en investigación clínica: La pregunta de investigación

Repertorio de Medicina y Cirugía, 2009
El proceso de la investigación en epidemiología requiere el reconocimiento de los elementos que lo constituyen, con el fin de alcanzar un desarrollo exitoso del mismo.
Ingrid Arévalo R., Merideidy Plazas V.
doaj   +1 more source

A 4D geometric morphometrics workflow to quantify complex biological motion

Methods in Ecology and Evolution, EarlyView.
Abstract Quantifying biological motion is fundamentally tied to quantifying the biological structures that produce that motion. Yet, this dependence makes it essential to decouple motion from static morphology to enable general, comparable analyses across individuals and conditions. In this work, we present a methodological pipeline to study biological
Marta Gómez‐Recio, Markus Bastir, Gael Deboeck, Antonella LoMauro, Andrea Aliverti, Véronique Feipel, Barbara Fischer, Philipp Mitteroecker, Benoit Beyer   +8 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source