Results 51 to 60 of about 25,575 (118)

Evolution of Endoscopic and Histologic Assessment of Eosinophilic Esophagitis in Europe and Evolution of the Diagnostic Delay: Data From the EUREOS EoE CONNECT Registry

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Endoscopy with histopathological assessment of esophageal biopsies is the cornerstone for the diagnosis and phenotypic characterization of eosinophilic esophagitis (EoE). Objective To evaluate temporal trends in endoscopic assessment and biopsy sampling practices for EoE in a large European cohort and their association with temporal
E. Grueso‐Navarro, E. Dilaghi, J. Fernández‐Pacheco, E. Amorena, E. V. Savarino, L. Blas‐Jhon, I. Pérez‐Martínez, A. Granja‐Navacerrada, D. Guagnozzi, L. Martín‐Asenjo, G. Pellegatta, M. Coletta, C. García‐Suárez, S. de la Riva, L. de la Peña‐Negro, E. Betoré, A. L. Krarup, J. Barrio, M. Votto, L. Bujanda, S. Fernández‐Fernández, J. E. Naves, A. González‐Almeida, R. Honrubia‐López, S. Carrión, S. Oliva, C. Caño‐Cerdán, M. L. Masiques‐Mas, S. Espina‐Cadena, J. González‐Cervera, S. Casabona‐Francés, J. Nicolay‐Maneru, V. Úbeda‐Vargas, M. Ghisa, P. Romo‐de Arriba, C. Donado, A. Benagues, V. Martín‐Domínguez, O. Nantes‐Castillejo, L. Arias‐González, D. Maniero, H. Moreira‐González, I. Maray, J. Barrio‐Torres, M. T. Pérez‐Fernández, M. Ostiz‐Llanos, L. Rodríguez‐Alcolado, A. M. Cabrera‐Martínez, E. J. Laserna‐Mendieta, C. Santander, A. J. Lucendo   +50 more
wiley   +1 more source

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 3, Page 395-405, September 2026.
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo, M. Palacio, C. Rueda, M. Larroya, D. Boada, J. Ponce, M. Guilleumes, O. Gómez, S. Ferrero, E. Gratacós, F. Crispi, T. Cobo   +11 more
wiley   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

Clinical &Experimental Allergy, Volume 56, Issue 9, Page 1048-1062, September 2026.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos, Chen‐Yuan Chiang, M. Innes Asher, Guy B. Marks, Asma El Sony, Refiloe Masekela, Karen Bissell, Eamon Ellwood, Philippa Ellwood, Neil Pearce, David P. Strachan, A. Elena Martínez‐Torres, Manuel Sánchez‐Solís, Kevin Mortimer, Eva Morales, The Global Asthma Network Phase I Study Group   +15 more
wiley   +1 more source

Durability of response to icotrokinra for high‐impact site psoriasis: 1‐year ICONIC‐TOTAL findings

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1502-1514, September 2026.
Participants with at least moderate scalp, genital or hand/foot psoriasis receiving once‐daily oral icotrokinra achieved high, durable rates of overall and high‐impact site psoriasis clearance, showed substantial nail psoriasis improvement and exhibited no safety signals through 1 year, supporting icotrokinra use for long‐term management of high‐impact
Richard B. Warren, Melinda Gooderham, Edward Lain, Robert Bissonnette, Yu‐Huei Huang, Julien Ringuet, Matthias Hoffmann, Andreas Pinter, Joseph F. Merola, Jessica H. Rubens, Dorothy Fan, Ming‐Chun Hsu, Shu Li, Ya‐Wen Yang, Cynthia M. C. DeKlotz, Eingun James Song   +15 more
wiley   +1 more source

Etica e investigación clínica.

ARS Medica, 2018
Sin ...
Andrés Valdivieso Dávila
doaj  

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz, Eugènia Pujol, Cristian Ramos, Valeria Rizzo, Christophe Morisseau, Cristina Val, Tiziana Ginex, Javier Vázquez, Sandra Codony, Andreea L. Turcu, Belén Pérez, Elena Sáez, Antonio Pineda‐Lucena, Bruce D. Hammock, F. Javier Luque, M. Isabel Loza, José Brea, Santiago Vázquez   +17 more
wiley   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Red académica de Seguridad Alimentaria. Revolucionando la Seguridad Alimentaria en las Américas a través de la Investigación Colaborativa y la Innovación

Práctica Familiar Rural
Introducción: La seguridad alimentaria se alcanza cuando todas las personas en todo momento tienen acceso físico y económico a alimentos seguros, suficientes y nutritivos, siendo esta un importante determinante de bienestar y desarrollo de las ...
Yadira Morejón-Terán, Andrés Viteri-García, Daniel Simancas-Racines   +2 more
doaj   +1 more source

[The use of Bayes factor in clinical cardiology research]. [PDF]

Rev Esp Cardiol, 2021
Ramos-Vera CA.
europepmc   +1 more source

[Clinical investigation and informed consent form in times of COVID-19 pandemic. A vision from the committee ethics of research]. [PDF]

Med Clin (Barc), 2021
Cervera Barajas A, Saldaña Valderas M.
europepmc   +1 more source