Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
El método clínico frente a las nuevas tecnologías
El desarrollo de la técnica en las Ciencias Médica pudiera llevar a la falsa idea de que en esta época de tanto adelanto tecnológico el interrogatorio, el examen físico minucioso, el diagnóstico de síntomas y signos, el planteamiento de síndromes y de ...
José Alberto Alfonso +2 more
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Meis A., Castellano A., Pinilla J.F ., El dinamismo del encuentro entre Dios y el Hombre en los comentarios al « Cantar de los Cantares » de Origenes, Gregorio de Nisa y Juan de la Cruz , coll. Investigaciones, Santiago, Ed. Universidad Católica de Chile, 2000, 23x16, 245 p. ISBN 956-14-0570-9 [PDF]
openalex +1 more source
Field-Assisted and Thermionic Contributions to Conductance in SnO2 Thick-Films [PDF]
A deep analysis of conductance in nanostructured SnO2 thick films has been performed. A model for field-assisted thermionic barrier crossing is being proposed to explain the film conductivity.
Aldao, Celso Manuel +5 more
core +1 more source
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente +5 more
wiley +1 more source
The natural history of nonalcoholic fatty liver disease: mortality rates and liver enzymes [PDF]
Nonalcoholic fatty liver disease (NAFLD) has emerged as an important health issue of the modern world, due to the dramatic increase in its prevalence, which has doubled and in some regions tripled in the past decade.
Pirola, Carlos José +1 more
core +1 more source
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner +8 more
wiley +1 more source
Effects of Incubation and Rearing Temperatures on Caiman latirostris Growth [PDF]
Different studies found that incubation temperature has an influence on the size of Caiman latirostris hatchlings and determines their gonadal sex. Experimental manipulations revealed that the effects of temperature on growth are independent of sex ...
Larriera, Alejandro +3 more
core
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
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