Results 241 to 250 of about 12,004,584 (291)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Inflammatory exacerbation of hepatic alveolar echinococcosis during dupilumab therapy: A case report. [PDF]

IDCases
Hasebe T, Tanaka H, Abe M, Hasebe C, Otake S, Hayashi H, Ota Y, Sawada K, Mizukami S, Takahashi H, Kitada M, Sako Y, Sakata A, Yuzawa S, Yokoo H.   +14 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

West Nile virus neuroinvasive disease and cardiac involvement in critically ill patients in central Italy: a case series. [PDF]

Front Med (Lausanne)
Tetaj N, Bocci MG, Capecchi G, Lesci A, Rubino D, Sabatini V, Taloni G, Mattiucci E, Ascoli T, Maffongelli G, De Marco P, Moschella Orsini F, Burocchi S, Albarello F, Ianniello S, Villanacci A, Nocioni M, Del Borgo C, Nania FA, Petrosillo N, Vairo F, Nicastri E.   +21 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Integrated BLV surveillance in Kazakhstan, 2025: diagnostic complementarity and risk zoning. [PDF]

Front Vet Sci
Mamanova S, Kassenov M, Nurpeisova A, Kaimoldina S, Bashenova E, Karabassova A, Kirpichenko V, Akshalova P, Ikramkulova F, Kassen A, Tulepov B, Turkeyev M, Abay Z, Serikov M, Zhetpisbay Z, Yussupov M, Akhmetsadykov N, Imanbekova T, Zakarya K, Rametov N, Nissanova R.   +20 more
europepmc   +1 more source

Pushing the boundaries - perioperative risk assessment and short-term surgical outcomes in octogenarian patients with head and neck cancer: comparison with non-oncological elderlies. [PDF]

Front Oncol
Wierzbicka M, Świątek D, Makuszewska M, Niemczyk K, Dżaman K, Czerwaty K, Mikaszewski B, Stodulski D, Kawczyński M, Rękawek M, Wierzchowska M, Burduk P, Sroka K, Pietruszewska W, Ciuba K, Markowski J.   +15 more
europepmc   +1 more source

Analysis of <i>PIK3CA</i> mutations in the lysate of sentinel lymph nodes in patients with early breast cancer. [PDF]

Front Oncol
Park SA, Masunaga N, Kin T, Tokui R, Sato Y, Mishima C, Yoshinami T, Tsukabe M, Sota Y, Tanei T, Shimazu K.   +10 more
europepmc   +1 more source

A multicentre observational study on landiolol use, efficacy, and safety in European patients with supraventricular arrhythmia (Landi-UP). [PDF]

Eur Heart J Acute Cardiovasc Care
Dizdarevic AM, Šramko M, Mangner N, Merkely B, Zima E, Nikolaos N, Scherr D, Knotzer J, Köglberger P, Nouvaki Z, Martinek M, Hnat T, Bethlehem C, Fras Z, Goździk W, Kotanidou A, Dąbrowski W, Lesiak M, Stefanska-Wronka K, Unger M, Sus J, Klade C, Krejcy K, Bouvet O, Oravec E, Krumpl G, Siller-Matula J.   +26 more
europepmc   +1 more source