Results 171 to 180 of about 2,151,663 (314)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Order Effect: Investigating Prompt Sensitivity to Input Order in LLMs

As large language models (LLMs) become integral to diverse applications, ensuring their reliability under varying input conditions is crucial. One key issue affecting this reliability is order sensitivity, wherein slight variations in the input arrangement can lead to inconsistent or biased outputs.
Guan, Bryan, Roosta, Tanya, Passban, Peyman, Rezagholizadeh, Mehdi   +3 more
openaire   +2 more sources

Automated Observability Investigation of Analog Electronic Circuits using SPICE

, 2011
In the present paper, a computer-aided approach to fault observability investigation of linear analog circuits is developed. The method is based on sensitivity investigation of the test characteristics in the frequency domain.
Atanasov, Anton, Gadjeva, Elissaveta, Shikalanov, Dimitar   +2 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A perspective and demonstration of an approach to screening synthetic nucleic acid orders containing short nucleic acid sequences. [PDF]

Front Bioeng Biotechnol
Gemler BT, Flyangolts K, Diggans J, Wittmann BJ, Fullerton PA, Seltzer MJ, Bartling C.   +6 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A New Method for Precisely Designing the Spiral Structure of an SDD with Optimal Electrical Properties. [PDF]

Micromachines (Basel)
Song X, Zhao J, Long T, Ni C, Li X, Liu M, Zhu X, Liu Z, Li Z.   +8 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Investigation of wolbachia spp in some flies species (order: diptera) by pcr [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2014
ŞAKİ CE, ŞİMŞEK S
doaj   +1 more source

Retraction Note: Fractional-order fast terminal sliding mode control of a nonlinear aeroelastic wing section considering gust load. [PDF]

Sci Rep
Xu XZ.
europepmc   +1 more source