Results 71 to 80 of about 2,151,663 (314)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A new numerical investigation of fractional order susceptible-infected-recovered epidemic model of childhood disease

Alexandria Engineering Journal, 2022
The susceptible-infected-recovered (SIR) epidemic model of childhood disease is analyzed in the present framework with the help of q-homotopy analysis transform method (q-HATM).
P. Veeresha, Esin Ilhan, D.G. Prakasha, Haci Mehmet Baskonus, Wei Gao   +4 more
doaj   +1 more source

The Independent Consultation and Investigation Mechanism: 2012 Annual Report [PDF]

, 2013
During 2012, the Independent Consultation and Investigation Mechanism (ICIM) carried out a range of activities and reached a number of important milestones that provided a wealth of lessons learned. The IDB Board of Executive Directors\u27 strong support
Inter-American Development Bank
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

REXS contribution to electronic ordering investigation in solids [PDF]

The European Physical Journal Special Topics, 2012
Resonant Elastic X-Ray Scattering (REXS) has played a fundamental role in understanding electronic properties and in revealing hidden order, local symmetries and exotic states realized in correlated solids. This article reports on some of the relevant scientific contributions and technical advances over the last 20 years, by providing a list of related
Beale, T.A.W., Beutier, G., Bland, S.R., Bombardi, A., Bouchenoire, L., Bunau, O., Di Matteo, Sergio, Fernandez-Rodriguez, J., Hamann-Borrero, J.E., Herrero-Martin, J., Jacques, V.L.R., Johnson, R.D., Juhin, A., Matsumura, T., Mazzoli, C., Mulders, A.M., Nakao, H., Okamoto, J., Partzsch, S., Princep, A.J., Scagnoli, V., Strempfer, J., Vecchini, C., Wakabayashi, Y., Walker, H.C., Wermeille, D., Yamasaki, Y.   +26 more
openaire   +7 more sources

An adaptive aeroelastic control approach using non linear reduced order models [PDF]

, 2014
A systematic approach to the model order reduction of high fidelity coupled fluid/structure/flight dynamics models and the subsequent control design is described. It uses information on the eigenspectrum of the coupled-system Jacobian matrix and projects
Palacios, R., Da Ronch, A., Gai, G, Kenneth J. Badcock, Guanqun Gai, Palacios, R, Tantaroudas, N.D., Tantaroudas, ND, Andrea Da Ronch, Gai, G., Da Ronch, A, Badcock, KJ, Nikolaos D. Tantaroudas, Badcock, K.J.   +13 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source