Results 31 to 40 of about 365,889 (298)

Double Jeopardy of Article 102 TFEU and the DMA – the Challenges of a Multi-Level Enforcement System

Utrecht Law Review
This article addresses the complexities and challenges of enforcing Article 102 TFEU and the Digital Markets Act in the context of the principles of ne bis in idem and proportionality under Articles 50 and 52(1) of the Charter of Fundamental Rights of ...
Veerle Peters, Małgorzata Kozak
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Navigating Public International Law: ECB Banking Supervision and Cross-border On-site Inspections

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(3), 579-606 | Article | (Table of Contents) 1. Introduction. – 2. ECB supervision of banks. – 3. On-site visits, extraterritorial enforcement and international law.
Anneloes Kuiper, Lucas Roorda, Cedric Ryngaert   +2 more
doaj   +1 more source

A very brief history of interception [PDF]

, 2016
Britain is in the process of legislating a new system of control over the interception of communication. The Investigatory Powers Bill, currently being debated in draft form, aims to give an unprecedented level of transparency and accountability to the ...
Keenan, Brendan
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Institutionalized Fact Finding at the WTO [PDF]

, 2006
This short article argues that the WTO should have a standing agency to conduct fact finding in order to correct evidentiary deficiencies in submissions by members to panels during dispute settlement.
Collins, D. A.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Will digital innovators say bye bye Britain? [PDF]

, 2015
LSE’s Alison Powell discusses the implications of the proposed Investigatory Powers Bill outlined in last week’s Queen’s Speech for the UK’s tech startup ...
Alison, Powell
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source