Results 61 to 70 of about 1,151,460 (302)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Trans Nzoia County Investment Guide 2013 [PDF]
Transnzoia County is the undisputed destiny to investors. The cosmopolitan county is strategically positioned in the region and offers a welcoming investment climate including abundant natural resources and competitive workforce, rapidly developing ...
core
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
What drives firms' investment in climate change? [PDF]
High energy prices in Europe and uncertainty caused by the Ukraine war are testing EU firms’ ability to invest in climate change measures. Europe urgently needs to embrace the transition to green energy, and firms will be called upon to play a pivotal
EUROPEAN INVESTMENT BANK
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Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Texas Workforce Investment Council Briefing Materials [PDF]
Briefing materials compiled for a meeting of the Texas Workforce Investment Council held December 5, 2013 at the Grand Hyatt Hotel, in San Antonio, Texas. The materials include agendas, minutes, and memoranda for members to consider related to the Texas
Texas Workforce Investment Council
core +6 more sources
The combined cooling, heating, and power system (CCHP) boasts efficient energy use and flexible operation. The CCHP integrated system for energy storage battery was designed, with the refined mathematical models of the key components established, and the
Fuguo ZHANG +4 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source

